Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

Lidocaine is an amide local anaesthetic initially used intravenously as an antiarrhythmic
agent. At some point it was proposed that intravenous lidocaine (IVL) had an analgesic …

The incidence and mortality of breast cancer (BC) have increased in recent years, and BC is
the main cause of cancer-related death in women worldwide. One of the most significant …

Local anesthetics are widely used during clinical cancer surgeries. Studies have suggested
that the use and the type of anesthesia affect cancer outcomes. In vivo studies and clinical …

A wide body of evidence suggests that voltage-gated sodium channels (VGSCs) are
expressed de novo in several human carcinomas where channel activity promotes a variety …

Breast cancer is the most common cancer among women and is considered a developed
country disease. Moreover, is a heterogenous disease, existing different types and stages of …

The use of local anesthetics during surgical treatment of cancer patients is an important part
of perioperative analgesia. In recent years, it has been showed that local anesthetics can …

Cancer is a leading contributor to deaths worldwide. Surgery is the primary treatment for
resectable cancers. Nonetheless, it also results in inflammatory response, angiogenesis …

While cancer treatment has improved dramatically, it has also encountered many critical
challenges, such as disease recurrence, metastasis, and drug resistance, making new drugs …

Cancer is a major global health problem and the second leading cause of death worldwide.
When detected early, surgery provides a potentially curative intervention for many solid …