[HTML][HTML] Galectin-3's Complex Interactions in Pancreatic Ductal Adenocarcinoma: From Cellular Signaling to Therapeutic Potential

M Dimitrijevic Stojanovic, B Stojanovic, I Radosavljevic… - Biomolecules, 2023 - mdpi.com
Galectin-3 (Gal-3) plays a multifaceted role in the development, progression, and prognosis
of pancreatic ductal adenocarcinoma (PDAC). This review offers a comprehensive …

[HTML][HTML] Prognostic and diagnostic significance of galectins in pancreatic cancer: a systematic review and meta-analysis

Q Sun, Y Zhang, M Liu, Z Ye, X Yu, X Xu, Y Qin - Cancer cell international, 2019 - Springer
Background Galectins constitute a family of β-galactoside-binding proteins, which influence
various hallmarks of pancreatic cancer, including cell proliferation, invasion and migration; …

[HTML][HTML] KIT Mutations Correlate with Higher Galectin Levels and Brain Metastasis in Breast and Non-Small Cell Lung Cancer

AT Funkhouser, AM Strigenz, BB Blair, AP Miller… - Cancers, 2022 - mdpi.com
Simple Summary Galectins are a family of β-galactoside binding proteins whose levels are
altered in various stages of different types of cancer. This study provides an analytical …

[HTML][HTML] Prognostic role of galectin-3 expression in patients with solid tumors: a meta-analysis of 36 eligible studies

Y Wang, S Liu, Y Tian, Y Wang, Q Zhang, X Zhou… - Cancer Cell …, 2018 - Springer
Background Galectin-3 as a β-galactoside-binding protein, has been found to be involved in
tumor cell growth, anti-apoptosis, adhesion, angiogenesis, invasion, and distant metastases …

[HTML][HTML] The inflammatory response of human pancreatic cancer samples compared to normal controls

KJ Brayer, JA Hanson, S Cingam, C Martinez, SA Ness… - Plos one, 2023 - journals.plos.org
Pancreatic ductal adenocarcinoma (PDAC) is a poor prognosis cancer with an aggressive
growth profile that is often diagnosed at late stage and that has few curative or therapeutic …

[HTML][HTML] Screening potential microRNAs associated with pancreatic cancer: Data mining based on RNA sequencing and microarrays

J Ma, S Sun, C Song, N Li, N Li… - Experimental and …, 2020 - spandidos-publications.com
Pancreatic cancer is a malignant tumor of the digestive tract, rendering it difficult to make an
accurate diagnosis. The 5 year survival rate for pancreatic cancer is< 1%, and surgical …

Predictive importance of galectin-3 for recurrence of non-small cell lung cancer

Y Kataoka, T Igarashi, Y Ohshio, T Fujita… - General thoracic and …, 2019 - Springer
Objective The predictive importance of galectin-3 in non-small cell lung cancer (NSCLC) has
not been elucidated. We examined whether galectin-3 could serve as a predictor for tumor …

[HTML][HTML] Relationship between circulating galectin-3, systemic inflammation, and protein-energy wasting in chronic hemodialysis patients

MT Tsai, SM Ou, HY Chen, WC Tseng, KH Lee… - Nutrients, 2021 - mdpi.com
Galectin-3 reportedly participates in the inflammatory process that causes insulin resistance
in the target tissues. However, the role of high plasma galectin-3 levels as an indicator of …

[HTML][HTML] Galectin-3 as the Prognostic Factor of Adverse Cardiovascular Events in Long-Term Follow up in Patients after Myocardial Infarction—A Pilot Study

P Święcki, R Sawicki, M Knapp, KA Kamiński… - Journal of Clinical …, 2020 - mdpi.com
Galectin-3 (Gal-3) is a new independent risk factor in the development and severity of
coronary artery disease (CAD). The aim of the study was to evaluate whether Gal-3 …

[HTML][HTML] Unveiling the potential of galectin-3 as a diagnostic biomarker for pancreatic cancer: a review

N Aderinto, MO Abdulbasit, D Olatunji… - Annals of Medicine and …, 2023 - journals.lww.com
Early detection of pancreatic cancer is crucial for improving patient outcomes, and
identifying reliable biomarkers is a critical research area in this field. Galectin-3 (Gal-3) is a …