[HTML][HTML] Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis

AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus

T Nuutinen - European journal of medicinal chemistry, 2018 - Elsevier
Cannabaceae plants Cannabis sativa L. and Humulus lupulus L. are rich in terpenes–both
are typically comprised of terpenes as up to 3–5% of the dry-mass of the female …

Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms

E Ramazani, M Akaberi, SA Emami… - Life Sciences, 2022 - Elsevier
Abstract Alpha-bisabolol (α-bisabolol), an unsaturated monocyclic sesquiterpene alcohol, is
known as one of the “most-used herbal constituents” in the world. Various therapeutic and …

[HTML][HTML] Health benefits, pharmacological effects, molecular mechanisms, and therapeutic potential of α-bisabolol

LB Eddin, NK Jha, SN Goyal, YO Agrawal… - Nutrients, 2022 - mdpi.com
α-Bisabolol is one of the important monocyclic sesquiterpenes, derived naturally from
essential oils of many edible and ornamental plants. It was first obtained from Matricaria …

CD73 in glioblastoma: Where are we now and what are the future directions?

NE Gelsleichter, JH Azambuja, DS Rubenich… - Immunology …, 2023 - Elsevier
Glioblastoma (GB) is the most aggressive type of brain tumor with heterogeneity, strong
invasive ability, and high resistance to therapy due to immunosuppressive mechanisms …

Cyclodextrin Conjugated α-Bisabolol Suppresses FAK Phosphorylation and Induces Apoptosis in Pancreatic Cancer

MT Kano, T Kokuryo, T Baba, K Yamazaki… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: α-Bisabolol is an essential oil component extracted from plants, such as
chamomile. We have previously reported that α-bisabolol suppressed proliferation, invasion …

Screening of phytochemicals from Clerodendrum inerme (L.) Gaertn as potential anti-breast cancer compounds targeting EGFR: an in-silico approach

N Yasmeen, A Ahmad Chaudhary… - Journal of …, 2023 - Taylor & Francis
Breast cancer (BC) is the most prevalent malignancy among women around the world. The
epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor (RTK) of the …

[HTML][HTML] Nanoformulation Shows Cytotoxicity against Glioblastoma Cell Lines and Antiangiogenic Activity in Chicken Chorioallantoic Membrane

DR Dallemole, T Terroso, ACS Alves, JN Scholl… - Pharmaceutics, 2021 - mdpi.com
Glioblastoma (GB) is a histological and genetically heterogeneous brain tumor that is highly
proliferative and vascularized. The prognosis is poor with currently available treatment. In …

[HTML][HTML] Modulation of adenosine receptors and antioxidative effect of beer extracts in in vitro models

P Alonso-Andrés, M Martín, JL Albasanz - Nutrients, 2019 - mdpi.com
The fight against neurodegenerative diseases is promoting the searching of nutrients,
preferably of wide consumption, with proven effects on health. Beer is widely consumed and …

A new investigational perspective for purines against glioblastoma invasiveness

P Giuliani, M Zuccarini, M Carluccio… - Current Drug …, 2018 - ingentaconnect.com
Background: Glioblastoma Multiforme (GBM) is the most common and lethal brain
malignancy. Recent evidence suggests that the presence of stem-like cells (GSCs) inside …