Associations of polypharmacy and inappropriate medications with adverse outcomes in older adults with cancer: a systematic review and meta‐analysis

MR Mohamed, E Ramsdale, KP Loh, A Arastu… - The …, 2020 - academic.oup.com
Background Polypharmacy (PP) and potentially inappropriate medications (PIM) are highly
prevalent in older adults with cancer. This study systematically reviews the associations of …

[HTML][HTML] Defining the expected 30-day mortality for patients undergoing palliative radiotherapy: A meta-analysis

JH Kutzko, P Dadwal, T Holt, MA Rahman… - Radiotherapy and …, 2022 - Elsevier
Background The expected 30-day mortality rate for patients treated with palliative radiation
is not established. The primary objective of this study is to define the proportion of patients …

Polypharmacy, Inappropriate Medication Use, and Drug Interactions in Older Korean Patients with Cancer Receiving First‐Line Palliative Chemotherapy

S Hong, JH Lee, EK Chun, KI Kim, JW Kim… - The …, 2020 - academic.oup.com
Background Polypharmacy is an important issue in the care of older patients with cancer, as
it increases the risk of unfavorable outcomes. We estimated the prevalence of …

The impact of polypharmacy on patient outcomes in older adults with cancer

G Nightingale, E Skonecki, MK Boparai - The Cancer Journal, 2017 - journals.lww.com
Polypharmacy is prevalent in older adults with cancer and may be advantageous for the
management of certain chronic disease states, but uncertainty exists regarding potential …

Polypharmacy and prescription medication use in a population-based sample of adolescent and young adult cancer survivors

AC Betts, CC Murphy, LA Shay… - Journal of Cancer …, 2023 - Springer
Purpose We examined prescription medication use and identified correlates of
polypharmacy—taking multiple medications—in adolescent and young adult cancer …

[HTML][HTML] Palliative radiation therapy in older adults with cancer: age-related considerations

A O'Donovan, L Morris - Clinical Oncology, 2020 - Elsevier
There are many additional considerations when treating older adults with cancer, especially
in the context of palliative care. Currently, radiation therapy is underutilised in some …

Polypharmacy in older adults with cancer undergoing radiotherapy: A review

J Novak, A Goldberg, K Dharmarajan, A Amini… - Journal of geriatric …, 2022 - Elsevier
Polypharmacy is characterized by the simultaneous use of multiple medications, including
prescription drugs, over-the-counter drugs, and nutritional supplements. Polypharmacy is …

[HTML][HTML] Lung cancer, comorbidities, and medication: the infernal trio

H Pluchart, S Chanoine, D Moro-Sibilot… - Frontiers in …, 2024 - frontiersin.org
Most patients with lung cancer are smokers and are of advanced age. They are therefore at
high risk of having age-and lifestyle-related comorbidities. These comorbidities are subject …

Polypharmacy in patients with ovarian cancer

S Oldak, S Ioannou, P Kamath, M Huang… - The …, 2019 - academic.oup.com
Objective Polypharmacy has been associated with morbidity and mortality in patients with
cancer. Data about polypharmacy among patients with ovarian cancer are limited. The …

[HTML][HTML] Influence of concomitant polypharmacy on docetaxel-induced febrile neutropenia

K Makihara, Y Shimeda… - Cancer Diagnosis & …, 2021 - ncbi.nlm.nih.gov
Results The total number of concomitant CYP3A4 inhibitors and substrates used was
significantly higher in patients with FN [mean: 2.1 (95% confidence interval (CI)= 1.5-2.9)] …