Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance

HS Tuli, S Mittal, D Aggarwal, G Parashar… - Seminars in Cancer …, 2021 - Elsevier
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained
enormous attention. The plausible reason and believe or mind set behind this fact is …

[HTML][HTML] Silymarin and cancer: A dual strategy in both in chemoprevention and chemosensitivity

D Delmas, J Xiao, A Vejux, V Aires - Molecules, 2020 - mdpi.com
Silymarin extracted from milk thistle consisting of flavonolignan silybin has shown
chemopreventive and chemosensitizing activity against various cancers. The present review …

The anticancer properties of silibinin: its molecular mechanism and therapeutic effect in breast cancer

A Binienda, S Ziolkowska… - Anti-Cancer Agents in …, 2020 - ingentaconnect.com
Background: Silibinin (SB), the main component of Silymarin (SM), is a natural substance
obtained from the seeds of the milk thistle. SM contains up to 70% of SB as two isoforms: A …

[HTML][HTML] TRAIL-sensitizing effects of flavonoids in cancer

A Luiz-Ferreira, T Pacifico, ÁC Cruz, F Laudisi… - International Journal of …, 2023 - mdpi.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) represents a promising
anticancer agent, as it selectively induces apoptosis in transformed cells without altering the …

Ursolic acid promotes the sensitization of rhTRAIL-resistant triple-negative breast cancer

JM Manouchehri, M Kalafatis - Anticancer research, 2018 - ar.iiarjournals.org
Background/Aim: Triple-negative breast cancer (TNBC) can be characterized as the
deadliest breast cancer type considering the lack of efficacious therapeutics. Recombinant …

Effects of sepantronium bromide (YM-155) on the whole transcriptome of MDA-MB-231 cells: Highlight on impaired ATR/ATM fanconi anemia DNA damage response

EA Mazzio, CA Lewis, R Elhag… - Cancer Genomics & …, 2018 - cgp.iiarjournals.org
Sepantronium bromide (YM-155) is believed to elicit apoptosis and mitotic arrest in tumor
cells by reducing (BIRC5, survivin) mRNA. In this study, we monitored changes in survivin …

Ablehnung einer konventionellen Therapie durch Patientinnen mit Mammakarzinom, die komplementäre und alternative Behandlungen anwendeten. Welche Gründe …

A Schleicherdt - 2021 - jlupub.ub.uni-giessen.de
Der aktuelle Forschungstand von Mammakarzinompatientinnen die alternative und
komplementäre Therapien anwenden und konventionelle Therapien ablehnten, ist …

RhTRAIL with Sensitizing Agents for Breast Carcinoma Treatment

JM Manouchehri - 2018 - rave.ohiolink.edu
Recombinant human tumor necrosis factor-related apoptosis-inducing ligand (rhTRAIL)
shows therapeutic potential for cancer with its ability to induce apoptosis in cancer cells …

[CITATION][C] The Future of Breast Cancer Treatment Relies on Getting in Touch with Mother Nature and Stepping Back on the TRAIL

JM Manouchehri, M Kalafatis - Clin Oncol, 2018