Cellular senescence is a complex biological process that leads to irreversible cell-cycle
arrest. Various extrinsic and intrinsic insults are associated with the onset of cellular …

DNA double-strand breaks (DSBs) are deleterious lesions that are generated in response to
ionizing radiation or replication fork collapse that can lead to genomic instability and cancer …

Osteosarcoma (OS) is a type of malignant primary bone cancer, which is highly aggressive
and occurs more commonly in children and adolescents. Thus, novel potential drugs and …

Emerging evidence indicates that lncRNAs play important roles in cancer tumourigenesis
and could be used as potential diagnostic biomarkers or therapeutic targets. However, the …

In order to maintain integrity of the genome, eukaryotic cells develop a complex DNA
damage/repair response network, which can induce cell cycle arrest, apoptosis, or DNA …

Long non-coding RNAs (lncRNAs) have been identified as master gene regulators through
various mechanisms such as transcription, translation, protein modification and RNA-protein …

Long non-coding RNAs (lncRNAs) constitute non-protein coding transcripts with a size>
than 200 nucleotides. They are involved in many cellular processes, such as chromatin …

Non-coding RNAs (ncRNAs) have been found to play essential roles in various
physiological and pathological processes. The involvement of ncRNAs in the development …

Objectives Long non‐coding RNA s (lnc RNA s) are characterized as a group of RNA s that
more than 200 nucleotides in length and have no protein‐coding function. More and more …

Diffuse large B-cell lymphoma (DLBCL) is one of the leading causes of cancer-related
mortality, and responds badly to existing treatment. Thus, it is of urgent need to identify novel …