Cervical cancer affects many women worldwide, with more than 500,000 cases diagnosed
and approximately 300,000 deaths each year. Resveratrol is a natural substance of the …

Background: Patient-derived xenograft (PDX) models have been a focus of attention
because they closely resemble the tumor features of patients and retain the molecular and …

Methionine dependence is due to the overuse of methionine for aberrant transmethylation
reactions in cancer. Methionine dependence may be the only general metabolic defect in …

Adoptive transfer of T cells engineered with a chimeric antigen receptor (CAR) is deemed as
the silver bullet to overcome the barriers of solid tumor treatment; however, the therapeutic …

Simple Summary The rate of total tumor engraftment of patient-derived xenografts is 50% in
cervical cancer. These cancers retain their histopathological characteristics. The gene …

Undifferentiated spindle‐cell sarcoma (USCS) is a recalcitrant cancer. Our laboratory
pioneered the patient‐derived orthotopic xenograft (PDOX) nude mouse model with the …

Simple Summary Cervical cancer is the fourth most commonly diagnosed cancer among
women worldwide. While treatments exist to stop growth of cervical cancer in humans, they …

Background/Aim: In the present study, we aimed to determine the efficacy of trabectedin
(TRAB) combined with oxaliplatinum (OXA)+ 5-fluorouracil (5-FU) on a colorectal cancer …

Purpose Cervical cancer is a recalcitrant disease. To help overcome this problem, we
previously established a patient-derived orthotopic xenograft (PDOX) model of cervical …

The circadian clock controls behavior and physiology. Presently, there is clear evidence of a
connection between this timing system and cancer development/progression. Moreover …