Immune‐pineal axis–acute inflammatory responses coordinate melatonin synthesis by pinealocytes and phagocytes

RP Markus, PA Fernandes, GS Kinker… - British journal of …, 2018 - Wiley Online Library
Melatonin is well known for its circadian production by the pineal gland, and there is a
growing body of data showing that it is also produced by many other cells and organs …

[HTML][HTML] Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity

RL McIntyre, YJ Liu, M Hu, BJ Morris, BJ Willcox… - Ageing research …, 2022 - Elsevier
Life expectancy has increased substantially over the last 150 years. Yet this means that now
most people also spend a greater length of time suffering from various age-associated …

Worldwide melatonin research: a bibliometric analysis of the published literature between 2015 and 2019

R Zakaria, A Ahmi, AH Ahmad… - Chronobiology …, 2021 - Taylor & Francis
This study presents a bibliometric analysis of the publications on melatonin research from
the Scopus database during the period 2015–2019. Based on the keywords used, which are …

[HTML][HTML] Field rates of Sivanto (flupyradifurone) and Transform® (sulfoxaflor) increase oxidative stress and induce apoptosis in honey bees (Apis mellifera L.)

P Chakrabarti, EA Carlson, HM Lucas… - Plos one, 2020 - journals.plos.org
Pesticide exposures can have detrimental impacts on bee pollinators, ranging from
immediate mortality to sub-lethal impacts. Flupyradifurone is the active ingredient in …

[HTML][HTML] Melatonin as a regulator of apoptosis in leukaemia: molecular mechanism and therapeutic perspectives

A Mafi, H Rismanchi, Y Gholinezhad… - Frontiers in …, 2023 - frontiersin.org
Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …

[HTML][HTML] Protein carbonylation and lipid peroxidation in hematological malignancies

A Rodríguez-García, R García-Vicente, ML Morales… - Antioxidants, 2020 - mdpi.com
Among the different mechanisms involved in oxidative stress, protein carbonylation and lipid
peroxidation are both important modifications associated with the pathogenesis of several …

[HTML][HTML] Mechanisms underlying tumor suppressive properties of melatonin

SC Bondy, A Campbell - International journal of molecular sciences, 2018 - mdpi.com
There is considerable evidence that melatonin may be of use in the prevention and
treatment of cancer. This manuscript will review some of the human, animal and cellular …

[HTML][HTML] Targeting mTOR in acute lymphoblastic leukemia

C Simioni, AM Martelli, G Zauli, E Melloni, LM Neri - Cells, 2019 - mdpi.com
Acute Lymphoblastic Leukemia (ALL) is an aggressive hematologic disorder and constitutes
approximately 25% of cancer diagnoses among children and teenagers. Pediatric patients …

[HTML][HTML] Melatonin improves quality of repeated-poor and frozen-thawed embryos in human, a prospective clinical trial

Z Bao, G Li, R Wang, S Xue, Y Zeng… - Frontiers in …, 2022 - frontiersin.org
Objective In this study, two experiments were performed to assess the effect and the role of
melatonin on human in vitro embryo quality. Methods Experiment I: A total of 42 repeated …

[HTML][HTML] Melatonin-induced changes in cytosolic calcium might be responsible for apoptosis induction in tumour cells

B Chovancova, S Hudecova, L Lencesova… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Melatonin is a hormone transferring information about duration of
darkness to the organism and is known to modulate several signaling pathways in the cells …