[HTML][HTML] Natural marine products: Anti-colorectal cancer in vitro and in vivo

N Han, J Li, X Li - Marine drugs, 2022 - mdpi.com
Colorectal cancer, a malignant tumor with high mortality, has a poor prognosis due to drug
resistance and toxicity in clinical surgery and chemotherapy. Thus, finding safer and more …

Therapeutic application of diverse marine-derived natural products in cancer therapy

CW Yun, HJ Kim, SH Lee - Anticancer Research, 2019 - ar.iiarjournals.org
Natural products (NPs) are useful sources of bioactive compounds and play important roles
in the development and discovery of new drugs for diverse human diseases. Most natural …

[HTML][HTML] Anti-colorectal cancer effects of seaweed-derived bioactive compounds

Y Fu, D Xie, Y Zhu, X Zhang, H Yue, K Zhu, Z Pi… - Frontiers in …, 2022 - frontiersin.org
Seaweeds are classified as Chlorophyta, Rhodophyta, and Phaeophyta. They constitute a
number of the most significant repositories of new therapeutic compounds for human use …

[HTML][HTML] Brown seaweed fucoidan in cancer: Implications in metastasis and drug resistance

ME Reyes, I Riquelme, T Salvo, L Zanella, P Letelier… - Marine Drugs, 2020 - mdpi.com
Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and
marine invertebrates. They have anti-cancer properties, through their targeting of several …

[HTML][HTML] Ten years of research on fucoidan and cancer: Focus on its antiangiogenic and antimetastatic effects

E Turrini, F Maffei, C Fimognari - Marine Drugs, 2023 - mdpi.com
Angiogenesis and metastasis represent two challenging targets to combat cancer
development in the later stages of its progression. Numerous studies have indicated the …

Melatonin promotes apoptosis of colorectal cancer cells via superoxide-mediated ER stress by inhibiting cellular prion protein expression

CW Yun, S Kim, JH Lee, SH Lee - Anticancer research, 2018 - ar.iiarjournals.org
Background/Aim: Melatonin, an endogenously secreted indoleamine hormone that is
produced in the pineal gland, is known to possess antitumor effect via various mechanisms …

[HTML][HTML] The role of cellular prion protein in cancer biology: a potential therapeutic target

M Ding, Y Chen, Y Lang, L Cui - Frontiers in Oncology, 2021 - frontiersin.org
Prion protein has two isoforms including cellular prion protein (PrPC) and scrapie prion
protein (PrPSc). PrPSc is the pathological aggregated form of prion protein and it plays an …

[HTML][HTML] The role of cellular prion protein in promoting stemness and differentiation in cancer

L Ryskalin, F Biagioni, CL Busceti, MA Giambelluca… - Cancers, 2021 - mdpi.com
Simple Summary Aside from its well-established role in prion disorders, in the last decades
the significance of cellular prion protein (PrPC) expression in human cancers has attracted …

[HTML][HTML] The role of cellular prion protein in immune system

S Cha, MY Kim - BMB reports, 2023 - ncbi.nlm.nih.gov
Numerous studies have investigated the cellular prion protein (PrP C) since its discovery.
These investigations have explained that its structure is predominantly composed of alpha …

[HTML][HTML] Prion protein in glioblastoma multiforme

L Ryskalin, CL Busceti, F Biagioni, F Limanaqi… - International journal of …, 2019 - mdpi.com
The cellular prion protein (PrPc) is an evolutionarily conserved cell surface protein encoded
by the PRNP gene. PrPc is ubiquitously expressed within nearly all mammalian cells …