Evidence is growing that the gut microbiota modulates the host response to
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …

Ulcerative colitis (UC) has closely been associated with an increased risk of colorectal
cancer. However, the exact mechanisms underlying colitis-associated cancer (CAC) …

The toll‐like receptor (TLR) family consists of vital receptors responsible for pattern
recognition in innate immunity, making them the core proteins involved in pathogen …

In the dark path of tumorigenesis, the more carefully the cancer biology is studied, the more
brilliant answers could be given to the countless questions about its orchestrating derivers …

Simple Summary Recent evidence indicates that opioids can be active at a receptor that is
abundantly expressed on innate immune cells as well as cancer cells: the receptor is termed …

Microbiota and its induced inflammation in colorectal mucosa have been considered risk
factors for the development of colorectal carcinogenesis. Previous studies demonstrated that …

The hypothesis that links the increase in the intake of plant-source foods to a decrease in
colorectal cancer (CRC) risk has almost 50 years. Nowadays, systematic reviews and meta …

Neuroinflammatory response in spinal dorsal horn has been demonstrated to be a critical
factor in oxaliplatin-induced pain. Melatonin has been shown to have anti-inflammatory and …

Simple Summary Colorectal cancer (CRC) is the second cause of cancer death worldwide.
Irinotecan is a drug widely used in CRC treatment. Unfortunately, colonic bacteria …

Resistin, a proinflammatory cytokine, is elevated in a number of pathological disorders,
including cancer. The serum resistin level in colon cancer patients is elevated and correlates …