[HTML][HTML] ELF3, ELF5, EHF and SPDEF transcription factors in tissue homeostasis and cancer

IY Luk, CM Reehorst, JM Mariadason - Molecules, 2018 - mdpi.com
The epithelium-specific ETS (ESE) transcription factors (ELF3, ELF5, EHF and SPDEF) are
defined by their highly conserved ETS DNA binding domain and predominant epithelial …

[HTML][HTML] Potential therapeutic applications of N-cadherin antagonists and agonists

OW Blaschuk - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
This review focuses on the cell adhesion molecule (CAM), known as neural (N)-cadherin
(CDH2). The molecular basis of N-cadherin-mediated intercellular adhesion is discussed, as …

E74 like ETS transcription factor 3 (ELF3) is a negative regulator of epithelial-mesenchymal transition in bladder carcinoma

K Gondkar, K Patel, S Krishnappa, A Patil… - Cancer …, 2019 - content.iospress.com
BACKGROUND: Transcription factors are commonly deregulated in various cancers. Here,
we evaluated role of ELF3 in pathogenesis of bladder carcinoma (BCa). MATERIALS AND …

ELF3 is an antagonist of oncogenic-signalling-induced expression of EMT-TF ZEB1

D Liu, Y Skomorovska, J Song, E Bowler… - Cancer biology & …, 2019 - Taylor & Francis
Background: Epithelial-to-mesenchymal transition (EMT) is a key step in the transformation
of epithelial cells into migratory and invasive tumour cells. Intricate positive and negative …

ELF3 overexpression as prognostic biomarker for recurrence of stage II colorectal cancer

A Takaoka, T Ishikawa, S Okazaki, S Watanabe, F Miya… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: Adjuvant chemotherapy for high-risk Stage II colorectal cancer (CRC) is
weakly recommended; however, no consensus exists on “high-risk” definition. Prognostic …

[HTML][HTML] ESE1 expression correlates with neuronal apoptosis in the hippocampus after cerebral ischemia/reperfusion injury

HL Yu, LZ Wang, LL Zhang, BL Chen… - Neural regeneration …, 2019 - journals.lww.com
Abstract Epithelial-specific ETS-1 (ESE1), a member of the ETS transcription factor family, is
widely expressed in multiple tissues and performs various functions in inflammation. During …

[HTML][HTML] ESE‑1 suppresses the growth, invasion and migration of human NSCLC cells and tumor formation in vivo

Z Lou, BS Lee, T Ha, Y Xu, HJ Kim… - Oncology …, 2018 - spandidos-publications.com
Lung cancer is the first leading cause of cancer‑related death in the United States. Non‑
small cell lung cancer (NSCLC) is the most common type of lung cancer and is associated …

The role of the ETS factor ELF3 in the normal and malignant prostate

LK Archer - 2018 - etheses.whiterose.ac.uk
The ETS transcription factor family members are involved in multiple cancers, including
prostate cancer. Whilst extensive literature exists on the highly prevalent TMPRSS2-ERG …

ESE1 表达与脑缺血再灌注损伤后海马神经元的凋亡相关

HL Yu, LZ Wang, LL Zhang, BL Chen… - 中国神经再生研究 …, 2019 - sjzsyj.com.cn
ESE1 是ETS 转录因子家族的成员, 在许多组织中广泛表达, 且在炎症反应中起多种作用.
以往研究表明ESE1 在神经炎症过程中可促进神经元凋亡, 但其在脑缺血过程中的表达及对神经 …