Application of 3D cultured multicellular spheroid tumor models in tumor-targeted drug delivery system research
BW Huang, JQ Gao - Journal of controlled release, 2018 - Elsevier
Tumor-targeted drug delivery systems are promising for their advantages in enhanced tumor
accumulation and reduced toxicity towards normal organs. However, few nanomedicines …
accumulation and reduced toxicity towards normal organs. However, few nanomedicines …
3D cultures for modeling nanomaterial-based photothermal therapy
Photothermal therapy (PTT) is one of the most promising techniques for cancer tumor
ablation. Nanoparticles are increasingly being investigated for use with PTT and can serve …
ablation. Nanoparticles are increasingly being investigated for use with PTT and can serve …
RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery
F Pi, H Zhang, H Li, V Thiviyanathan… - … , Biology and Medicine, 2017 - Elsevier
A novel modified nucleic acid nanoparticle harboring an annexin A2 aptamer for ovarian
cancer cell targeting and a GC rich sequence for doxorubicin loading is designed and …
cancer cell targeting and a GC rich sequence for doxorubicin loading is designed and …
Advances in the study of spheroids as versatile models to evaluate biological interactions of inorganic nanoparticles
RBL Henrique, RRM Lima, CAP Monteiro, WF Oliveira… - Life Sciences, 2022 - Elsevier
Spheroids are in vitro three-dimensional multicellular microstructures able to mimic the
biological microenvironment, including the complexity of tumor architecture. Therefore …
biological microenvironment, including the complexity of tumor architecture. Therefore …
Zinc oxide nanoparticle–poly I: C RNA complexes: Implication as therapeutics against experimental melanoma
M Ramani, MC Mudge, RT Morris, Y Zhang… - Molecular …, 2017 - ACS Publications
There is current interest in harnessing the combined anticancer and immunological effect of
nanoparticles (NPs) and RNA. Here, we evaluate the bioactivity of poly I: C (pIC) RNA …
nanoparticles (NPs) and RNA. Here, we evaluate the bioactivity of poly I: C (pIC) RNA …
Determinants of alanine dipeptide conformational equilibria on graphene and hydroxylated derivatives
H Poblete, I Miranda-Carvajal… - The Journal of Physical …, 2017 - ACS Publications
Understanding the interaction of carbon nanomaterials with proteins is essential for
determining the potential effects of these materials on health and in the design of …
determining the potential effects of these materials on health and in the design of …
Comparative functional dynamics studies on the enzyme nano-bio interface
Introduction Biomedical applications of nanoparticles (NPs) as enzyme inhibitors have
recently come to light. Oxides of metals native to the physiological environment (eg, Fe, Zn …
recently come to light. Oxides of metals native to the physiological environment (eg, Fe, Zn …
[HTML][HTML] Two-dimensional fluorescence difference spectroscopy of ZnO and Mg composites in the detection of physiological protein and RNA interactions
Two-dimensional fluorescence difference spectroscopy (2-D FDS) was used to determine
the unique spectral signatures of zinc oxide (ZnO), magnesium oxide (MgO), and 5 …
the unique spectral signatures of zinc oxide (ZnO), magnesium oxide (MgO), and 5 …
Nanoscale Material Interaction with Multicellular 3D Cancer Culture
E Darrigues - 2020 - search.proquest.com
Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer; it
is difficult to diagnose, often recurs, has high resistance to chemotherapies, and can be …
is difficult to diagnose, often recurs, has high resistance to chemotherapies, and can be …