The aim of this study is to determine and critically evaluate the plausible relationships of
vitamin D with extra-skeletal tissues in humans. Severe vitamin D deficiency results in rickets …

The objective was to provide the current state of the art regarding the role of vitamin D in
chronic diseases (osteoporosis, cancer, cardiovascular diseases, dementia, autism, type 1 …

Research carried out during the past two-decades extended the understanding of actions of
vitamin D, from regulating calcium and phosphate absorption and bone metabolism to many …

The genomic actions of the vitamin D are mediated via its biologically most potent metabolite
1α, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the transcription factor vitamin D receptor …

In the last two decades vitamin D (VD) research has demonstrated new extraskeletal actions
of this pre-hormone, suggesting a protective role of this secosteroid in the onset, progression …

Ultraviolet B (UVB), in addition to having carcinogenic activity, is required for the production
of vitamin D3 (D3) in the skin which supplies> 90% of the body's requirement. Vitamin D is …

Nutritional supplements are widely used among patients with cancer who perceive them to
be anticancer and antitoxicity agents. Depending on the type of malignancy and the gender …

Nonmelanoma skin cancers including basal and squamous cell carcinomas (SCC and BCC)
represent a significant clinical problem due to their relatively high incidence, imposing an …

Global cancer incidence and mortality rates are high and increasing. Thus, it is imperative to
find novel solutions to preventing cancer incidence and treating it at an affordable yet …

Melanoma represents a significant clinical problem affecting a large segment of the
population with a relatively high incidence and mortality rate. Ultraviolet radiation (UVR) is …