Small molecules regulating reactive oxygen species homeostasis for cancer therapy
J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
A role of gallic acid in oxidative damage diseases: A comprehensive review
J Gao, J Hu, D Hu, X Yang - Natural Product …, 2019 - journals.sagepub.com
Gallic acid is a trihydroxybenzoic acid of plant metabolites widely spread throughout the
plant kingdom. It has characteristics of the strong antioxidant and free radical scavenging …
plant kingdom. It has characteristics of the strong antioxidant and free radical scavenging …
Gallic acid and gallates in human health and disease: do mitochondria hold the key to success?
Gallic acid and gallate esters are widely used as dietary supplements or additives with
clinical significances. Over the last few decades, a large number of publications have been …
clinical significances. Over the last few decades, a large number of publications have been …
Gallic acid: A dietary polyphenol that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
Phytochemicals are being used for thousands of years to prevent dreadful malignancy. Side
effects of existing allopathic treatment have also initiated intense research in the field of …
effects of existing allopathic treatment have also initiated intense research in the field of …
Photosensitized methyl paraben induces apoptosis via caspase dependent pathway under ambient UVB exposure in human skin cells
Methyl paraben (MP), is a widely used preservative in pharmaceutical, food and cosmetic
products. Its molecular mechanism under ambient ultraviolet radiation is not well …
products. Its molecular mechanism under ambient ultraviolet radiation is not well …
[HTML][HTML] Tunicamycin Induces Hepatic Stellate Cell Apoptosis Through Calpain-2/Ca2 +-Dependent Endoplasmic Reticulum Stress Pathway
H Liu, L Dai, M Wang, F Feng, Y Xiao - Frontiers in Cell and …, 2021 - frontiersin.org
It has been reported that calpain/caspase-mediated apoptosis induced by endoplasmic
reticulum stress (ERS) in hepatic stellate cells (HSCs) by previous studies. At present, the …
reticulum stress (ERS) in hepatic stellate cells (HSCs) by previous studies. At present, the …
[HTML][HTML] Gallnuts: a potential treasure in anticancer drug discovery
J Gao, X Yang, W Yin, M Li - Evidence-Based Complementary and …, 2018 - hindawi.com
Introduction. In the discovery of more potent and selective anticancer drugs, the research
continually expands and explores new bioactive metabolites coming from different natural …
continually expands and explores new bioactive metabolites coming from different natural …
[HTML][HTML] Could dantrolene be explored as a repurposed drug to treat COVID-19 patients by restoring intracellular calcium homeostasis?
B Jiang, S Liang, G Liang, H Wei - European review for medical …, 2020 - ncbi.nlm.nih.gov
Dantrolene, an FDA approved drug to treat malignant hyperthermia and muscle spasm, has
been demonstrated to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
been demonstrated to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
[HTML][HTML] Mapping pharmacological network of multi-targeting litchi ingredients in cancer therapeutics
S Cao, Y Han, Z Su - Frontiers in Pharmacology, 2020 - frontiersin.org
Considerable pharmacological studies have demonstrated that the extracts and ingredients
from different parts (seeds, peels, pulps, and flowers) of Litchi exhibited anticancer effects by …
from different parts (seeds, peels, pulps, and flowers) of Litchi exhibited anticancer effects by …
Galangin induces p53-independent S-phase arrest and apoptosis in human nasopharyngeal carcinoma cells through inhibiting PI3K–AKT signaling pathway
CC Lee, ML Lin, M Meng, SS Chen - Anticancer Research, 2018 - ar.iiarjournals.org
Background/Aim: Anti-cancer activity of 3, 5, 7-trihydroxyflavone (galangin) has been
documented in a variety of cancer types; however, its effect on human nasopharyngeal …
documented in a variety of cancer types; however, its effect on human nasopharyngeal …