Role of mitochondria in liver metabolic health and diseases

B Morio, B Panthu, A Bassot, J Rieusset - Cell Calcium, 2021 - Elsevier
The liver is a major organ that coordinates the metabolic flexibility of the whole body, which
is characterized by the ability to adapt dynamically in response to fluctuations in energy …

[HTML][HTML] The role of ARF family proteins and their regulators and effectors in cancer progression: a therapeutic perspective

C Casalou, A Ferreira, DC Barral - Frontiers in cell and …, 2020 - frontiersin.org
The Adenosine diphosphate-Ribosylation Factor (ARF) family belongs to the RAS
superfamily of small GTPases and is involved in a wide variety of physiological processes …

Deranged hepatocyte intracellular Ca2+ homeostasis and the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma

ES Ali, GY Rychkov, GJ Barritt - Cell calcium, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in
men, and the sixth in women. Non-alcoholic fatty liver disease (NAFLD) is now one of the …

Low levels of microsatellite instability at simple repeated sequences commonly occur in human hepatocellular carcinoma

C Goumard, C Desbois-Mouthon… - Cancer genomics & …, 2017 - cgp.iiarjournals.org
Background/Aim: The aim of this study was to assess the incidence of MSI in a large series
of human hepatocellular carcinomas (HCC) with various etiologies. Materials and Methods …

KDM5B promotes self‐renewal of hepatocellular carcinoma cells through the microRNA‐448–mediated YTHDF3/ITGA6 axis

JC Guo, Z Liu, YJ Yang, M Guo… - Journal of Cellular …, 2021 - Wiley Online Library
Histone methylation plays important roles in mediating the onset and progression of various
cancers, and lysine‐specific demethylase 5B (KDM5B), as a histone demethylase, is …

[HTML][HTML] Comprehensive analysis of the lncRNA‑associated competing endogenous RNA network in breast cancer

JJ Wang, YQ Huang, W Song, YF Li… - Oncology …, 2019 - spandidos-publications.com
Long noncoding RNAs (lncRNAs) have been confirmed to be potential prognostic markers
in a variety of cancers and to interact with microRNAs (miRNAs) as competing endogenous …

[HTML][HTML] Genomic profiling and network-level understanding uncover the potential genes and the pathways in hepatocellular carcinoma

SA El-Kafrawy, MM El-Daly, LH Bajrai… - Frontiers in …, 2022 - frontiersin.org
Data integration with phenotypes such as gene expression, pathways or function, and
protein-protein interactions data has proven to be a highly promising technique for …

Integrin alpha 6 is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex

G Zheng, H Bouamar, M Cserhati… - … journal of cancer, 2022 - Wiley Online Library
Abstract Integrin α6 (ITGA6) forms integrin receptors with either integrin β1 (ITGB1) or
integrin β4 (ITGB4). How it functions to regulate hepatocellular carcinoma (HCC) …

[HTML][HTML] Expression and diagnostic value of miR-497 and miR-1246 in hepatocellular carcinoma

S Chen, Z Fu, S Wen, X Yang, C Yu, W Zhou… - Frontiers in …, 2021 - frontiersin.org
Objective Serum microRNAs (miRNAs) may serve as biomarkers in various cancers. Our
study aims to explore the roles of miR-497 and miR-1246 in hepatocellular carcinoma …

[HTML][HTML] Identification of hub genes in hepatocellular carcinoma using integrated bioinformatic analysis

S Hua, Z Ji, Y Quan, M Zhan, H Wang, W Li, Y Li… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The molecular mechanisms underlying hepatocellular carcinoma (HCC) progression remain
largely undefined. Here, we identified 176 commonly upregulated genes in HCC tissues …