[HTML][HTML] Prognostic factors for recurrence in pituitary adenomas: recent progress and future directions

L Lu, X Wan, Y Xu, J Chen, K Shu, T Lei - Diagnostics, 2022 - mdpi.com
Pituitary adenomas (PAs) are benign lesions; nonetheless, some PAs exhibit aggressive
behaviors, which lead to recurrence. The impact of pituitary dysfunction, invasion-related …

Farnesol abrogates epithelial to mesenchymal transition process through regulating Akt/mTOR pathway

JH Lee, A Chinnathambi, SA Alharbi, OHM Shair… - Pharmacological …, 2019 - Elsevier
Epithelial mesenchymal transition (EMT) refers to a phenomenon through which epithelial
cells develop the metastatic and invasive potential, which are closely related to …

[HTML][HTML] Tumor-associated macrophages: new horizons for pituitary adenoma researches

C Han, S Lin, X Lu, L Xue, ZB Wu - Frontiers in endocrinology, 2021 - frontiersin.org
Macrophages are one of the most common infiltrating immune cells and an essential
component of tumor microenvironment. Macrophages and the soluble cytokines and …

[HTML][HTML] ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway

J Wang, Z Zhang, R Li, F Mao, W Sun, J Chen… - Biomedicine & …, 2018 - Elsevier
Pituitary adenomas are the second most common primary brain tumor with invasive
properties. We have previously identified that ADAM12 (a disintegrin and metalloprotease …

[HTML][HTML] Regulating the CCNB1 gene can affect cell proliferation and apoptosis in pituitary adenomas and activate epithelial‑to‑mesenchymal transition

B Li, HB Zhu, GD Song, JH Cheng, CZ Li… - Oncology …, 2019 - spandidos-publications.com
The aim of the present study was to investigate the role and potential regulatory
mechanisms of cyclin B1 (CCNB1) in the proliferation, apoptosis and epithelial‑to …

Estrogen Receptor α, a Sex-Dependent Predictor of Aggressiveness in Nonfunctioning Pituitary Adenomas: SSTR and Sex Hormone Receptor Distribution in NFPA

KA Øystese, O Casar-Borota… - The Journal of …, 2017 - academic.oup.com
Abstract Context Nonfunctioning pituitary adenomas (NFPAs) are fairly common and require
a multidisciplinary approach. Reliable markers of a clinically aggressive course are lacking …

[HTML][HTML] Epithelial–mesenchymal transition in the resistance to somatostatin receptor ligands in acromegaly

J Gil, M Jordà, B Soldevila - Frontiers in Endocrinology, 2021 - frontiersin.org
Epithelial-mesenchymal transition (EMT) is a dynamic process by which epithelial cells loss
their phenotype and acquire mesenchymal traits, including increased migratory and invasive …

[HTML][HTML] PDCD10 promotes the aggressive behaviors of pituitary adenomas by up-regulating CXCR2 and activating downstream AKT/ERK signaling

J Liu, J Wang, W Tian, Y Xu, R Li, K Zhao, C You… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
As the second most common primary intracranial neoplasms, about 40% of pituitary
adenomas (PAs) exhibit aggressive behaviors and resulting in poor patient prognosis. The …

A systematic review of molecular alterations in invasive non-functioning pituitary adenoma

N Hosseinkhan, M Honardoost, Z Emami, S Cheraghi… - Endocrine, 2022 - Springer
Purpose Invasive non-functional pituitary adenomas (NFPAs) constitute 35% of NFPAs.
Despite a relatively large body of molecular investigations on the invasiveness of NFPA, the …

[HTML][HTML] Hypoxia, but Not Normoxia, Reduces Effects of Resveratrol on Cisplatin Treatment in A2780 Ovarian Cancer Cells: A Challenge for Resveratrol Use in …

A Synowiec, K Brodaczewska, G Wcisło… - International Journal of …, 2023 - mdpi.com
Natural compounds, such as resveratrol (Res), are currently used as adjuvants for
anticancer therapies. To evaluate the effectiveness of Res for the treatment of ovarian …