The multiple uses of fluorescent proteins to visualize cancer in vivo

RM Hoffman - Nature Reviews Cancer, 2005 - nature.com
Naturally fluorescent proteins have revolutionized biology by enabling what was formerly
invisible to be seen clearly. These proteins have allowed us to visualize, in real time …

AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms

S Naghibi, T Chen, A Jamshidi Ghahfarokhi… - Aggregate, 2021 - Wiley Online Library
Proteins are the building blocks of life, regarded as one of the most complex and crucial
biomacromolecules in biological systems, and playing a significant role in executing genes …

[HTML][HTML] GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosis

JS Chang, CY Su, WH Yu, WJ Lee, YP Liu, TC Lai… - Oncotarget, 2015 - ncbi.nlm.nih.gov
G-protein-coupled receptor kinase interacting protein 1 (GIT1) is participated in cell
movement activation, which is a fundamental process during tissue development and cancer …

[HTML][HTML] Comparison of the selective targeting efficacy of Salmonella typhimurium A1-R and VNP20009 on the Lewis lung carcinoma in nude mice

Y Zhang, N Zhang, M Zhao, RM Hoffman - Oncotarget, 2015 - ncbi.nlm.nih.gov
Salmonella typhimurium A1-R is auxotrophic for arg and leu, which attenuates growth in
normal tissue but allows high tumor targeting and virulence. A1-R is effective against …

Fluorescence‐guided surgery of human prostate cancer experimental bone metastasis in nude mice using anti‐CEA DyLight 650 for tumor illumination

S Miwa, N De Magalhães, M Toneri… - Journal of …, 2016 - Wiley Online Library
The present report demonstrates efficacy of fluorescence‐guided surgery (FGS) to resect
and prevent recurrence of experimental skeletal metastasis in a nude‐mouse model of …

The advantages of using fluorescent proteins for in vivo imaging

RM Hoffman - Current Protocols Essential Laboratory …, 2017 - Wiley Online Library
Fluorescent proteins have revolutionized biology by enabling what was formerly invisible to
be seen clearly, and potentially enable imaging of all cells in living animals. There are …

Real-time non-invasive spectral imaging of orthotopic red fluorescent protein-expressing lung tumor growth in nude mice

Y Zhang, N Zhang, M Zhao, RM Hoffman - Anticancer Research, 2015 - ar.iiarjournals.org
Background/Aim. Orthotopic implantation of cancer allows metastasis to occur. The most
patient-like metastatic orthotopic models are developed with surgical orthotopic implantation …

Methods for Tumor Targeting with Salmonella typhimurium A1-R

RM Hoffman, M Zhao - Bacterial Therapy of Cancer: Methods and …, 2016 - Springer
Abstract Salmonella typhimurium A1-R (S. typhimurium A1-R) has shown great preclinical
promise as a broad-based anti-cancer therapeutic (please see Chapter 1). The present …