The measurement of estrogens is important for diagnosing and monitoring the health of
women, men, and children. For example, for postmenopausal women or women undergoing …

Niemann–Pick disease type C (NPC) is an autosomal recessive disease caused by a
functional deficiency of cholesterol-transporting proteins in lysosomes, and exhibits various …

Neurosteroids have been associated with neurodegenerative diseases because they are
involved in the modulation of neurotransmitter, neurotropic and neuroprotective actions …

Objectives: To assess sex hormones in men with obesity and prostate cancer (PCa) and to
study association between androgens and the pathogenesis biology of PCa in vitro …

Substantial preclinical data suggest estrogen's carcinogenic role in prostate cancer
development; however, epidemiological evidence based on circulating estrogen levels is …

The plasma membrane (PM) is considered as a major druggable site. More than 50% of the
existing drugs target PM proteins. In the wake of emerging data indicating a key role of …

Androgen-metabolizing enzymes convert cholesterol, a relatively inert molecule, into some
of the most potent chemical messengers in vertebrates. This conversion involves …

Background There is evidence that obesity is associated with an aggressive prostate cancer
(PC). Furthermore, preclinical studies suggest that oestrogens may play a pivotal role in this …