The multiple uses of fluorescent proteins to visualize cancer in vivo

RM Hoffman - Nature Reviews Cancer, 2005 - nature.com
Naturally fluorescent proteins have revolutionized biology by enabling what was formerly
invisible to be seen clearly. These proteins have allowed us to visualize, in real time …

[HTML][HTML] Benefits of functional assays in personalized cancer medicine: More than just a proof-of-concept

CBM du Puch, M Vanderstraete, S Giraud… - Theranostics, 2021 - ncbi.nlm.nih.gov
As complex and heterogeneous diseases, cancers require a more tailored therapeutic
management than most pathologies. Recent advances in anticancer drug development …

Gynecologic and breast cancers: what's new in chemoresistance and chemosensitivity tests?

JC Marcolin, M Lichtenfels, CA da Silva… - Current Problems in …, 2023 - Elsevier
Gynecological and breast cancers affect women's health worldwide. Although chemotherapy
is one of the principal treatments for cancer, it also has limitations owing to toxicity and tumor …

[HTML][HTML] The identification of candidate effective combination regimens for pancreatic cancer using the histoculture drug response assay

E Jun, Y Park, W Lee, J Kwon, S Lee, MB Kim, JS Lee… - Scientific reports, 2020 - nature.com
The prognosis for patients with pancreatic cancer is extremely poor, as they are resistant to
first line chemotherapy. The long-term goal of this study was to identify effective combination …

Clinical significance of the histoculture drug response assay in breast cancer

Y Shinden, Y Kijima, M Hirata, H Arima… - Anticancer …, 2016 - ar.iiarjournals.org
Background/Aim: Despite the fact that breast cancer patients are generally administered
systemic chemotherapy after surgical treatment, predictive factors that allow optimization of …

Predicting the risk of new cerebral lesions after stereotactic radiosurgery (SRS) for brain metastases from breast cancer

L Dziggel, M Dahlke, S Janssen, D Hornung… - Anticancer …, 2015 - ar.iiarjournals.org
Aim: To generate a tool that estimates the probability of developing new cerebral metastases
after stereotactic radiosurgery (SRS) in breast cancer patients. Patients and Methods: SRS …

Collagen gel droplet-embedded culture drug sensitivity test for adjuvant chemotherapy after complete resection of non-small-cell lung cancer

M Inoue, H Maeda, Y Takeuchi, K Fukuhara, Y Shintani… - Surgery Today, 2018 - Springer
Purpose We conducted a prospective clinical study to individualize adjuvant chemotherapy
after complete resection of non-small-cell lung cancer (NSCLC), based on the drug …

Clinical usefulness of the histoculture drug response assay for breast cancer

RM Hoffman, H Tanino - 3D Sponge-Matrix Histoculture: Methods and …, 2018 - Springer
The histoculture drug response assay (HDRA) was used to compare drug sensitivity of
recurrent and primary breast cancer in vitro as well as in the clinic. The HDRA utilizes 3 …

Expression and Targeting of Tumor Markers in Gelfoam® Histoculture: Potential Individualized Assays for Immuno-Oncology

RM Hoffman, F Guadagni - 3D Sponge-Matrix Histoculture: Methods and …, 2018 - Springer
Tumor-specific antigens are important in the study of tumor biology, tumor diagnosis, and
prognosis and as targets for tumor therapy. This chapter reviews patient colon, breast, and …