[HTML][HTML] Broad targeting of resistance to apoptosis in cancer

RM Mohammad, I Muqbil, L Lowe, C Yedjou… - Seminars in cancer …, 2015 - Elsevier
Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

Potential anticancer properties and mechanisms of action of curcumin

NG Vallianou, A Evangelopoulos, N Schizas… - Anticancer …, 2015 - ar.iiarjournals.org
Curcumin, a yellow substance belonging to the polyphenols superfamily, is the active
component of turmeric, a common Indian spice, which is derived from the dried rhizome of …

[HTML][HTML] Designing a broad-spectrum integrative approach for cancer prevention and treatment

KI Block, C Gyllenhaal, L Lowe, A Amedei… - Seminars in cancer …, 2015 - Elsevier
Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …

Systemic treatment with resveratrol and/or curcumin reduces the progression of experimental periodontitis in rats

MG Corrêa, PR Pires, FV Ribeiro… - Journal of …, 2017 - Wiley Online Library
Background and Objective Periodontitis is a chronic inflammatory disease of periodontal
tissues that leads to the destruction of bone and other connective tissues. Resveratrol and …

Importance of thymoquinone, sulforaphane, phloretin, and epigallocatechin and their health benefits

MH Shahrajabian, W Sun - Letters in Drug Design & Discovery, 2024 - ingentaconnect.com
Natural products have a broad diversity of multidimensional chemical formations, which play
an important role, and indicate the crucial nature as a golden source for gaining herbal drug …

Role of dietary bioactive natural products in estrogen receptor-positive breast cancer

MJ Bak, SD Gupta, J Wahler, N Suh - Seminars in cancer biology, 2016 - Elsevier
Estrogen receptor (ER)-positive breast cancer, including luminal-A and-B, is the most
common type of breast cancer. Extended exposure to estrogen is associated with an …

Molecular mechanisms of action and chemosensitization of tumor cells in ovarian cancer by phytochemicals: A narrative review on pre‐clinical and clinical studies

JR Barboza, FAN Pereira… - Phytotherapy …, 2023 - Wiley Online Library
Ovarian cancer is the second‐leading cause of death among women with cancer of the
genital tract. Currently, drugs derived from platinum and taxanes constitute the majority of …

[HTML][HTML] A broad-spectrum integrative design for cancer prevention and therapy

KI Block, C Gyllenhaal, L Lowe, A Amedei… - Seminars in cancer …, 2015 - ncbi.nlm.nih.gov
Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …

Licochalcone A induces apoptotic cell death via JNK/p38 activation in human nasopharyngeal carcinoma cells

CY Chuang, CM Tang, HY Ho, CH Hsin… - Environmental …, 2019 - Wiley Online Library
Licochalcone A is widely studied in different fields and possesses antiasthmatic,
antibacterial, anti‐inflammatory, antioxidative, and anticancer properties. Its antimalignancy …

[HTML][HTML] Oridonin effectively reverses cisplatin drug resistance in human ovarian cancer cells via induction of cell apoptosis and inhibition of matrix metalloproteinase …

S Ma, W Tan, B Du, W Liu, W Li… - Molecular …, 2016 - spandidos-publications.com
Cisplatin is a first generation platinum‑based chemotherapeutic agent, however, the
extensive application of cisplatin inevitably results in drug resistance, which is a major …