DNA‐Targeted Metallodrugs: An Untapped Source of Artificial Gene Editing Technology
DNA binding metal complexes are synonymous with anticancer drug discovery. Given the
array of structural and chemical reactivity properties available through careful design, metal …
array of structural and chemical reactivity properties available through careful design, metal …
[PDF][PDF] Platinum antitumor complexes: 50 years since Barnett Rosenberg's discovery
FM Muggia, A Bonetti, JD Hoeschele… - J. Clin …, 2015 - researchgate.net
Journal of Clinical Oncology recently featured the dramatic changes that took place within
the last 50 years resulting in transforming malignant germ cell testicular tumors from highly …
the last 50 years resulting in transforming malignant germ cell testicular tumors from highly …
[HTML][HTML] Diplatin, a Novel and Low-Toxicity Anti-Lung Cancer Platinum Complex, Activation of Cell Death in Tumors via a ROS/JNK/p53-Dependent Pathway, and a …
X Lin, Y Jia, X Dong, J Shen, Y Jin, Y Li… - Frontiers in …, 2019 - frontiersin.org
Background: Platinum-based drugs prevail as the main treatment of lung cancer; this is
caused by their relative effectiveness despite known side effects, such as neurotoxicity. The …
caused by their relative effectiveness despite known side effects, such as neurotoxicity. The …
The properties of cholesterol-modified pullulan nanoparticles with different PEG coatings and their anti-hepatoblastoma cell effects
X Tian, X He, A Yao, Y You, F Yang, K Chen… - Materials …, 2022 - Taylor & Francis
Hydrophobically modified amino-pullulan polymers (CHPNH2) were modified with
polyethylene glycol (PEG) through the connective arms of succinic anhydride (SA) and cis …
polyethylene glycol (PEG) through the connective arms of succinic anhydride (SA) and cis …
[HTML][HTML] Identification and Characterization of Approved Drugs and Drug-Like Compounds as Covalent Escherichia coli ClpP Inhibitors
E Sassetti, C Durante Cruz, P Tammela… - International journal of …, 2019 - mdpi.com
The serine protease Caseinolytic protease subunit P (ClpP) plays an important role for
protein homeostasis in bacteria and contributes to various developmental processes, as well …
protein homeostasis in bacteria and contributes to various developmental processes, as well …
Diplatin, a novel water-soluble platinum complex, inhibits lung cancer growth via augmentation of Fas-mediated apoptosis
L Wang, X Zeng, J Ye, X Chen, X Lin - European Journal of Pharmacology, 2020 - Elsevier
Platinum drugs, such as cisplatin (DDP) and carboplatin (CBP), are the main drugs for the
treatment of lung cancer, but their practical clinical application is limited by severe toxicity …
treatment of lung cancer, but their practical clinical application is limited by severe toxicity …
[PDF][PDF] Chapter-2 Platinum and its complexes as Anticancer Agents Author name: Dhananjay Das
D Das - CHEMICAL SCIENCES, 2020 - researchgate.net
River”. 1, 2 The electronic configuration of Pt atom is [Xe] 4f145d96s1and consider as a
noble metal. Platinum is a less reactive metal and it has an extraordinary resistance to …
noble metal. Platinum is a less reactive metal and it has an extraordinary resistance to …
[PDF][PDF] Novos complexos de paládio (II) contendo tiossemicarbazonas: citotoxicidade, estudos de interação com proteínas e avaliação do potencial antitumoral
AB Lazzarini - 2019 - repositorio.unesp.br
O câncer é a segunda doença mais fatal e onera em US $1, 16 trilhão/ano. Seu tratamento
tem como base os quimioterápicos baseados em platina (II), em destaque, a cisplatina. Em …
tem como base os quimioterápicos baseados em platina (II), em destaque, a cisplatina. Em …
[CITATION][C] Le terapie anti-tumorali a base di farmaci analoghi del platino
A Bonetti, J Giuliani, F Muggia - Recenti Progressi in Medicina, 2015 - recentiprogressi.it
Le terapie anti-tumorali a base di farmaci analoghi del platino | Recenti Progressi in Medicina
Caricamento... Recenti Progressi in Medicina Presentazione Comitato Scientifico Norme …
Caricamento... Recenti Progressi in Medicina Presentazione Comitato Scientifico Norme …