Reactive oxygen species and gastric carcinogenesis: The complex interaction between Helicobacter pylori and host

S Wu, Y Chen, Z Chen, F Wei, Q Zhou, P Li… - Helicobacter, 2023 - Wiley Online Library
Helicobacter pylori (H. pylori) is a highly successful human pathogen that colonizes stomach
in around 50% of the global population. The colonization of bacterium induces an …

Crosstalk between DNA damage and inflammation in the multiple steps of gastric carcinogenesis

O Sokolova, M Naumann - … , resolution and escape by Helicobacter pylori, 2019 - Springer
Over the last years, intensive investigations in molecular biology and cell physiology
extended tremendously the knowledge about the association of inflammation and cancer. In …

[HTML][HTML] Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo

H Huang, S Park, H Zhang, S Park, W Kwon… - Journal of Experimental …, 2021 - Springer
Background Colorectal cancer (CRC) is a clinically challenging malignant tumor worldwide.
As a natural product and sesquiterpene lactone, Costunolide (CTD) has been reported to …

Synergistic antiproliferative effects of curcumin and celecoxib in hepatocellular carcinoma HepG2 cells

FM Abdallah, MW Helmy, MA Katary… - … archives of pharmacology, 2018 - Springer
Hepatocellular carcinoma (HCC) is still a leading cancer killer in the community. Molecular
targeted therapy with celecoxib (CXB) has shown promising antitumor effects; however, its …

[HTML][HTML] Significance of AKT in gastric cancer

T Sasaki, H Kuniyasu - international journal of oncology, 2014 - spandidos-publications.com
AKT is a serine/threonine kinase activated downstream of integrin, which is a receptor for
various pro‑proliferation and bioactive substances as well as the extracellular matrix …

FAM3B promotes progression of oesophageal carcinoma via regulating the AKT–MDM2–p53 signalling axis and the epithelial‐mesenchymal transition

SL He, WP Wang, YS Yang, EM Li… - Journal of Cellular …, 2019 - Wiley Online Library
FAM3B has been suggested to play important roles in the progression of many cancers,
such as gastric, oral, colon and prostate cancer. However, little is known about the role of …

Comprehensive Overview of 2022 Human Monkeypox Outbreak and Its Pathology, Prevention, and Treatment: A Strategy for Disease Control

MH Yashavarddhan, D Bohra, R Rana, HS Tuli… - Microbiological …, 2023 - Elsevier
The 2022 Monkeypox virus, an evolved DNA strain originating in Africa, exhibits heightened
human-to-human transmissibility and potential animal transmission. Its host remains …

[HTML][HTML] Braf mutation is associated with hyperplastic polyp-associated gastric cancer

R Fujiwara-Tani, A Okamoto, H Katsuragawa… - International Journal of …, 2021 - mdpi.com
Gastric hyperplastic polyps (GHP) are frequently found to be benign polyps and have been
considered to have a low carcinogenic potential. The characteristics of the hyperplastic …

[HTML][HTML] MicroRNA-224 aggrevates tumor growth and progression by targeting mTOR in gastric cancer

Y Zhang, CF Li, LJ Ma, M Ding… - … journal of oncology, 2016 - spandidos-publications.com
Growing evidence suggests that microRNA plays an essential role in the development and
metastasis of many tumors, including gastric cancer. Aberrant miR-224 expression has been …

[HTML][HTML] ADNP Upregulation Promotes Bladder Cancer Cell Proliferation via the AKT Pathway

S Zhu, Z Xu, Y Zeng, Y Long, G Fan, Q Ding… - Frontiers in …, 2020 - frontiersin.org
Background Activity-dependent neuroprotective protein (ADNP), which is involved in
embryonic development and neurogenesis, has been proven to be upregulated in some …