Natural biomacromolecules have attracted increased attention as carriers in biomedicine in
recent years because of their inherent biochemical and biophysical properties including …

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …

The emergence of drug-resistance and the low specificity of anticancer agents are the major
challenges in the treatment of cancer and can result in many side effects, creating an urgent …

The world is experiencing a cancer epidemic and an increase in the prevalence of the
disease. Cancer remains a major killer, accounting for more than half a million deaths …

Background: Artemisinin is a sesquiterpene lactone compound with a special peroxide
bridge that is tightly linked to the cytotoxicity involved in fighting malaria and cancer …

The development of new efficient therapeutics for the treatment of malaria and cancer is an
important endeavor. Over the past 15 years, much attention has been paid to the synthesis …

Background Breast cancer is a prominent cause of death among women worldwide. Recent
studies have demonstrated that artemisinin (ART) displays anti-tumor activity. Using a …

Artemisinin is a natural bioactive sesquiterpene lactone containing an unusual
endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia …

Considerable progress has been made with the rather recently developed dimer approach,
which has already found applications in the development of new effective artemisinin …

Background Patients with metastatic or relapsed gallbladder cancer generally have a poor
prognosis. Therefore, targeting metastasis is one arm of therapeutic strategies to treat …