[HTML][HTML] Adenovirus as a vector and oncolytic virus

W Matsunaga, A Gotoh - Current Issues in Molecular Biology, 2023 - mdpi.com
Adenoviral vectors, both oncolytic viruses and gene delivery vectors, are among the earliest
approved and commercialised vectors for gene therapy. Adenoviruses have high cytotoxicity …

[HTML][HTML] Oncolytic viral therapy for mesothelioma

DF Pease, RA Kratzke - Frontiers in oncology, 2017 - frontiersin.org
The limited effectiveness of conventional therapy for malignant pleural mesothelioma
demands innovative approaches to this difficult disease. Even with aggressive multimodality …

A novel fiber chimeric conditionally replicative adenovirus-Ad5/F35 for tumor therapy

M Yang, CS Yang, WW Guo, JQ Tang… - Cancer Biology & …, 2017 - Taylor & Francis
Significant progress has been made in the diagnosis and treatment of cancer; however,
significant challenges remain. Conditionally replicating adenoviruses (CRAds), which not …

[PDF][PDF] New diagnostic and therapeutic avenues for mesothelioma.

UZ Paracha, K Hayat, M Ali… - Pakistan Journal of …, 2015 - researchgate.net
Mesothelioma is a rare form of cancer affecting the mesothelium lining. It is usually caused
by asbestos exposure or exposure to nanofibers. Median survival is less than one year in …

Oncolytic virotherapy for human malignant mesothelioma: recent advances

N Boisgerault, C Achard, T Delaunay… - Oncolytic …, 2015 - Taylor & Francis
Cancer virotherapy is an attractive alternative to conventional treatments because it offers a
wide range of antitumor effects due to 1) the diversity of the oncolytic viruses that are now …

Cancer cell-specific gene disruption of VEGF-A using Cas9

W Matsunaga, A Gotoh - Personalized Medicine Universe, 2023 - jstage.jst.go.jp
Purpose: Angiogenesis inhibitor therapy for cancer is an efficient treatment as a" starvation
tactic" against tumor tissues. Angiogenesis inhibitors, such as bevacizumab (avastin), a …

Personalized medicine-based strategy for prostate cancer

A Gotoh - Personalized Medicine Universe, 2014 - Elsevier
With the emergence of molecularly targeted drugs, the phrase “personalized medicine” has
recently become frequently used in the medical community. This phrase basically refers to …

溶瘤单纯疱疹病毒介入治疗恶性肿瘤的临床疗效观察

高云东, 陈光利, 郭鹏德, 杨鑫磊 - 中华医学杂志, 2016 - cqvip.com
目的比较溶瘤单纯疱疹病毒OnceVex^ GM-CSF 与阿霉素治疗恶性肿瘤的疗效,
肿瘤标志物水平, 患者生活质量及不良反应, 为恶性肿瘤的介入治疗提供新方案 …

[PDF][PDF] 重组腺病毒 Ad5/F11p-GFP 对不同肿瘤细胞系感染效率的比较研究

曹晓培, 肖凤君, 高瞻, 杨月峰, 张群伟, 王立生… - 中国医药生物 …, 2015 - cmbp.net.cn
目的以Ad5-GFP 及Ad5/F35-GFP 为对照, 评价Ad5/F11p-GFP 对不同肿瘤细胞系的感染效率.
方法制备并纯化Ad5-GFP, Ad5/F11p-GFP 及Ad5/F35-GFP 三种重组腺病毒 …