Signaling pathways in inflammation and anti-inflammatory therapies

YT Yeung, F Aziz, A Guerrero-Castilla… - Current …, 2018 - ingentaconnect.com
During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

A targeted therapy for protein and lipid kinases in chronic lymphocytic leukemia

P Robak, T Robak - Current medicinal chemistry, 2012 - ingentaconnect.com
Protein kinases (PKs) and lipid kinases (LKs) are good choices for targets of signal
transduction therapy as these enzymes are involved in signaling pathways, and are often …

Ras signaling regulates stem cells and amelogenesis in the mouse incisor

X Zheng, AF Goodwin, H Tian… - Journal of dental …, 2017 - journals.sagepub.com
The role of Ras signaling during tooth development is poorly understood. Ras proteins—
which are activated by many upstream pathways, including receptor tyrosine kinase …

[HTML][HTML] Screening of PI3K-Akt-targeting Drugs for Silkworm against Bombyx mori Nucleopolyhedrovirus

B Wang, L Jiang, H Guo, Q Sun, Y Wang, E Xie, Q Xia - Molecules, 2019 - mdpi.com
Bombyx mori nucleopolyhedrovirus (BmNPV) is the most prevalent threat to silkworms.
Hence, there is a need for antiviral agents in sericulture. The PI3K-Akt pathway is essential …