[HTML][HTML] Tumor heterogeneity in breast cancer
G Turashvili, E Brogi - Frontiers in medicine, 2017 - frontiersin.org
Breast cancer is a heterogeneous disease and differs greatly among different patients
(intertumor heterogeneity) and even within each individual tumor (intratumor heterogeneity) …
(intertumor heterogeneity) and even within each individual tumor (intratumor heterogeneity) …
Clinical applications of the CellSearch platform in cancer patients
S Riethdorf, L O'Flaherty, C Hille, K Pantel - Advanced drug delivery …, 2018 - Elsevier
Abstract The CellSearch® system (CS) enables standardized enrichment and enumeration
of circulating tumor cells (CTCs) that are repeatedly assessable via non-invasive “liquid …
of circulating tumor cells (CTCs) that are repeatedly assessable via non-invasive “liquid …
Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data
FC Bidard, DJ Peeters, T Fehm, F Nolé… - The lancet …, 2014 - thelancet.com
Background We aimed to assess the clinical validity of circulating tumour cell (CTC)
quantification for prognostication of patients with metastatic breast cancer by undertaking a …
quantification for prognostication of patients with metastatic breast cancer by undertaking a …
Chemokines in triple-negative breast cancer heterogeneity: new challenges for clinical implications
Tumor heterogeneity is a hallmark of cancer and one of the primary causes of resistance to
therapies. Triple-negative breast cancer (TNBC), which accounts for 15–20% of all breast …
therapies. Triple-negative breast cancer (TNBC), which accounts for 15–20% of all breast …
Strategies for the discovery and development of therapies for metastatic breast cancer
BL Eckhardt, PA Francis, BS Parker… - Nature reviews Drug …, 2012 - nature.com
Nearly all deaths caused by solid cancers occur as a result of metastasis—the formation of
secondary tumours in distant organs such as the lungs, liver, brain and bone. A major …
secondary tumours in distant organs such as the lungs, liver, brain and bone. A major …
[HTML][HTML] Circulating MiR-125b as a marker predicting chemoresistance in breast cancer
H Wang, G Tan, L Dong, L Cheng, K Li, Z Wang, H Luo - PloS one, 2012 - journals.plos.org
Background Chemotherapy is an important component in the treatment paradigm for breast
cancers. However, the resistance of cancer cells to chemotherapeutic agents frequently …
cancers. However, the resistance of cancer cells to chemotherapeutic agents frequently …
[HTML][HTML] Longitudinal enumeration and cluster evaluation of circulating tumor cells improve prognostication for patients with newly diagnosed metastatic breast cancer …
AM Larsson, S Jansson, PO Bendahl… - Breast Cancer …, 2018 - Springer
Abstract Background Circulating tumor cells (CTCs) carry independent prognostic
information in patients with metastatic breast cancer (MBC) on different lines of therapy …
information in patients with metastatic breast cancer (MBC) on different lines of therapy …
Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance
YF Sun, XR Yang, J Zhou, SJ Qiu, J Fan… - Journal of cancer research …, 2011 - Springer
Abstract Background Circulating tumor cells (CTCs) have long been considered a reflection
of tumor aggressiveness. Hematogenous spreading of CTCs from a primary tumor is a …
of tumor aggressiveness. Hematogenous spreading of CTCs from a primary tumor is a …
[HTML][HTML] Circulating tumor cell status monitors the treatment responses in breast cancer patients: a meta-analysis
WT Yan, X Cui, Q Chen, YF Li, YH Cui, Y Wang… - Scientific reports, 2017 - nature.com
Whether circulating tumor cells (CTCs) can be used as an indicator of treatment response in
breast cancer (BC) needs to be clarified. We addressed this issue by a meta-analysis …
breast cancer (BC) needs to be clarified. We addressed this issue by a meta-analysis …
[HTML][HTML] CTC enumeration and characterization: moving toward personalized medicine
A Toss, Z Mu, S Fernandez… - Annals of translational …, 2014 - ncbi.nlm.nih.gov
The primary cause of tumor-related death in breast cancer (BC) is still represented by distant
metastasization. The dissemination of tumor cells from the primary tumor to distant sites …
metastasization. The dissemination of tumor cells from the primary tumor to distant sites …