[HTML][HTML] The clinical utilization of circulating cell free DNA (CCFDNA) in blood of cancer patients

YI Elshimali, H Khaddour, M Sarkissyan, Y Wu… - International journal of …, 2013 - mdpi.com
Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for
the management of malignant and benign neoplasms. Detecting circulating DNA in cancer …

How to stomach an epigenetic insult: the gastric cancer epigenome

N Padmanabhan, T Ushijima, P Tan - Nature reviews Gastroenterology …, 2017 - nature.com
Gastric cancer is a deadly malignancy afflicting close to a million people worldwide. Patient
survival is poor and largely due to late diagnosis and suboptimal therapies. Disease …

[HTML][HTML] Methylated circulating tumor DNA in blood: power in cancer prognosis and response

K Warton, KL Mahon, G Samimi - Endocrine-related cancer, 2016 - erc.bioscientifica.com
The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …

DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer

Y Toiyama, Y Okugawa, A Goel - Biochemical and biophysical research …, 2014 - Elsevier
Cancer initiation and progression is controlled by both genetic and epigenetic events.
Epigenetics refers to the study of mechanisms that alter gene expression without …

[HTML][HTML] DNA and histone methylation in gastric carcinogenesis

DQ Calcagno, CO Gigek, ES Chen… - World journal of …, 2013 - ncbi.nlm.nih.gov
Epigenetic alterations contribute significantly to the development and progression of gastric
cancer, one of the leading causes of cancer death worldwide. Epigenetics refers to the …

[HTML][HTML] Significant function and research progress of biomarkers in gastric cancer

DM Ye, G Xu, W Ma, Y Li, W Luo, Y Xiao… - Oncology …, 2020 - spandidos-publications.com
Gastric cancer is one of the most common gastrointestinal tumor types, and the incidence
and mortality rates are higher in men compared with women. Various studies have revealed …

[HTML][HTML] Diagnostic and prognostic value of circulating tumor DNA in gastric cancer: a meta-analysis

Y Gao, K Zhang, H Xi, A Cai, X Wu, J Cui, J Li, Z Qiao… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Circulating tumor DNA (ctDNA) has offered a minimally invasive approach for
detection and measurement of gastric cancer (GC). However, its diagnostic and prognostic …

[HTML][HTML] Challenges of deciphering gastric cancer heterogeneity

P Hudler - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer is in decline in most developed countries; however, it still accounts for a
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …

[HTML][HTML] Cell‑free DNA as a liquid biopsy for early detection of gastric cancer

ZB Huang, HT Zhang, B Yu, DH Yu - Oncology Letters, 2021 - spandidos-publications.com
Gastric cancer (GC) is one of the most common malignant tumors with poor prognosis
worldwide, mainly due to the lack of suitable modalities for population‑based screening and …

Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications

K Yamashita, S Sakuramoto, M Watanabe - Surgery today, 2011 - Springer
Abstract Knowledge about the molecular profile of tumor tissues is crucial to effectively target
cancer cells, because cancer is a genetic disease that involves multiple genetic and …