Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging
D Patterson, DC Cabelof - Mechanisms of ageing and development, 2012 - Elsevier
Down syndrome is a condition of intellectual disability characterized by accelerated aging.
As with other aging syndromes, evidence accumulated over the past several decades points …
As with other aging syndromes, evidence accumulated over the past several decades points …
Alternative RNA splicing and gastric cancer
Y Li, Y Yuan - Mutation Research/Reviews in Mutation Research, 2017 - Elsevier
Alternative splicing (AS) linked to diseases, especially to tumors. Recently, more and more
studies focused on the relationship between AS and gastric cancer (GC). This review …
studies focused on the relationship between AS and gastric cancer (GC). This review …
Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues
S Ohnuma, K Miura, A Horii, W Fujibuchi, N Kaneko… - Surgery, 2009 - Elsevier
BACKGROUND: Alternative splicing is a molecular mechanism by which different
combinations of exons can be alternatively spliced to produce different mRNA isoforms …
combinations of exons can be alternatively spliced to produce different mRNA isoforms …
Altered expression of the human base excision repair gene NTH1 in gastric cancer
M Goto, K Shinmura, H Igarashi, M Kobayashi… - …, 2009 - academic.oup.com
A base excision repair enzyme, NTH1, has activity that is capable of removing oxidized
pyrimidines, such as thymine glycol (Tg), from DNA. To clarify whether the NTH1 gene is …
pyrimidines, such as thymine glycol (Tg), from DNA. To clarify whether the NTH1 gene is …
[HTML][HTML] Development and validation of an individual alternative splicing prognostic signature in gastric cancer
S Lou, J Zhang, Z Zhai, X Yin, Y Wang, T Fang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Gastric cancer (GC) is a heterogeneous disease with different clinical manifestations and
prognoses. Alternative splicing (AS) is a determinant of gene expression and contributes to …
prognoses. Alternative splicing (AS) is a determinant of gene expression and contributes to …
[HTML][HTML] The landscape of alternative splicing reveals novel events associated with tumorigenesis and the immune microenvironment in gastric cancer
S Lou, J Zhang, Z Zhai, X Yin, Y Wang, T Fang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Alternative splicing (AS), contributing to vast protein diversity from a rather limited number of
genes in eukaryotic transcripts, has emerged as an important signature for tumor initiation …
genes in eukaryotic transcripts, has emerged as an important signature for tumor initiation …
Aberrant DNA polymerase beta promotes genomic instability associated with gastric carcinogenesis and innate immunity
S Zhao - 2022 - repositories.lib.utexas.edu
Base excision repair (BER) is critical to maintain cellular genomic stability. Several BER
genes, including DNA polymerase beta (Pol β), play an important role in tumor development …
genes, including DNA polymerase beta (Pol β), play an important role in tumor development …
Alternative splicing, DNA damage and modulating drugs in radiation therapy for cancer
JY Tang, RN Li, PH Chen, HW Huang… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
Radiotherapy effectively destroys cancer cells in many sites of the body, but several
limitations remain. This study investigated alternative splicing, which is a common …
limitations remain. This study investigated alternative splicing, which is a common …
染色體 1p32. 2-36.1 區域肝癌易感受基因連鎖高峰之定位: 候選基因策略
王雅蕙 - 2008 - tdr.lib.ntu.edu.tw
中文摘要背景: 在肝腫瘤組織的研究中已經常發現1 號染色體短臂(1p) 有高頻率染色體缺損現象.
先前利用微衛星標記針對肝細胞癌多發病例家族為研究樣本, 進行連鎖分析, 顯示在1p32. 2 …
先前利用微衛星標記針對肝細胞癌多發病例家族為研究樣本, 進行連鎖分析, 顯示在1p32. 2 …
[CITATION][C] Role of base excision repair enzyme MUTYH in the repair of 8-hydroxyguanine and MUTYH-associated polyposis (MAP)
K Shinmura - Hereditary Genetics, 2012 - cir.nii.ac.jp
Role of Base Excision Repair Enzyme MUTYH in the Repair of 8-Hydroxyguanine and
MUTYH-Associated Polyposis (MAP) | CiNii Research CiNii 国立情報学研究所 学術情報 …
MUTYH-Associated Polyposis (MAP) | CiNii Research CiNii 国立情報学研究所 学術情報 …