Recent developments in nucleic acid delivery with polyethylenimines
P Neuberg, A Kichler - Advances in genetics, 2014 - Elsevier
Polyethylenimines (PEIs) have proven to be highly efficient and versatile agents for nucleic
acid delivery in vitro and in vivo. Despite the low biodegradability of these polymers, they …
acid delivery in vitro and in vivo. Despite the low biodegradability of these polymers, they …
The role of the adeno-associated virus capsid in gene transfer
KM Van Vliet, V Blouin, N Brument… - Drug Delivery …, 2008 - Springer
Adeno-associated virus (AAV) is one of the most promising viral gene transfer vectors that
has been shown to effect long-term gene expression and disease correction with low toxicity …
has been shown to effect long-term gene expression and disease correction with low toxicity …
Efficacy of recombinant adeno-associated viral vectors serotypes 1, 2, and 5 for the transduction of pancreatic and colon carcinoma cells
C Teschendorf, B Emons, N Muzyczka… - Anticancer …, 2010 - ar.iiarjournals.org
Background: The development of efficient and specific vector systems remains a central
issue in gene therapy. Several different adeno-associated virus (AAV) serotypes have so far …
issue in gene therapy. Several different adeno-associated virus (AAV) serotypes have so far …
[HTML][HTML] Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events
Homologous recombination (HR) faithfully restores DNA double-strand breaks. Defects in
this HR repair pathway are associated with cancer predisposition. In genetic engineering …
this HR repair pathway are associated with cancer predisposition. In genetic engineering …
RNA 干扰 BC047440 基因表达对 HCT-8 细胞增殖能力的影响
唐亮， 赵权， 宫鹏涛， 李建华， 杨举， 张西臣 - 中国生物制品学杂志, 2010 - cqvip.com
目的探讨RNA 干扰结肠癌相关基因BC047440 的表达对结肠癌细胞HCT-8 增殖能力的影响.
方法将BC047440 基因shRNA 干扰质粒pGPU6/GFP/Neo-BC047440-331 (a1) …
方法将BC047440 基因shRNA 干扰质粒pGPU6/GFP/Neo-BC047440-331 (a1) …
Studies on viral gene transfer and angiogenesis inhibition in experimental glioma models
PC Huszthy - 2006 - bora.uib.no
The transduction patterns of recombinant adeno-associated virus serotype 1 (AAV1) and
serotype 6 (AAV6) vectors were assessed in human glioblastoma multiforme (GBM) cell …
serotype 6 (AAV6) vectors were assessed in human glioblastoma multiforme (GBM) cell …
Métodos de modificación génica dirigida en células humanas y su aplicación en el Síndrome de Wiskott-Aldrich
MA Bernardi - 2015 - uvadoc.uva.es
Generamos una línea celular reportera (RCL) en la que introdujimos una copia del gen
EGFP truncado en 3´. También generamos un virus adenoasociado recombinante (rAAV) …
EGFP truncado en 3´. También generamos un virus adenoasociado recombinante (rAAV) …
基因治疗大肠癌的研究进展
熊宇， 罗琪 - 现代生物医学进展, 2007 - cqvip.com
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