Several randomized prospective studies on breast cancer patients have proved the safety of
neoadjuvant chemotherapy. These trials have also demonstrated that tumor down staging …

Purpose To evaluate the potential of diffusion-weighted (DW) magnetic resonance (MR)
imaging with an apparent diffusion coefficient (ADC) map in the prediction of response to …

A major area of interest in nuclear medicine is the scintigraphic in vivo evaluation of complex
cellular processes involved in tumour growth, progression and response to treatment with …

BACKGROUND. This study investigated the role of magnetic resonance imaging (MRI) in
evaluation of pathologically complete response and residual tumors in patients who were …

Oestrogen receptor (ER) negative breast cancers are more likely to achieve a pathological
complete response (pCR) to neoadjuvant chemotherapy compared to those with ER positive …

Abstract Background and Objective: Chemotherapy is useful to many breast cancer patients,
however, it is not therapeutic for some patients. Pathologic complete response (pCR) is an …

Background Numerous studies have yielded inconclusive results regarding the relationship
between anti-apoptotic protein Bcl-2 expression and the sensitivity to chemotherapy in the …

Background Neoadjuvant chemotherapy (NAC) is widely used in advanced breast cancer
patients. However, there is little known about conversion frequency of estrogen receptor …

MicroRNAs (miRNAs) are small non-coding RNAs that are often located in genomic
breakpoint regions and play a critical role in regulating a variety of the cellular processes in …

Digital quantitative immunohistochemical analysis of protein biomarker expression offers a
broad dynamic range against which clinical outcomes may be measured. Semi-quantitative …