Molecular mechanisms of cisplatin resistance

L Galluzzi, L Senovilla, I Vitale, J Michels, I Martins… - Oncogene, 2012 - nature.com
Platinum-based drugs, and in particular cis-diamminedichloroplatinum (II)(best known as
cisplatin), are employed for the treatment of a wide array of solid malignancies, including …

[HTML][HTML] Systems biology of cisplatin resistance: past, present and future

L Galluzzi, I Vitale, J Michels, C Brenner… - Cell death & …, 2014 - nature.com
The platinum derivative cis-diamminedichloroplatinum (II), best known as cisplatin, is
currently employed for the clinical management of patients affected by testicular, ovarian …

The impact of radiation therapy on the antitumor immunity: local effects and systemic consequences

K Lumniczky, G Sáfrány - Cancer letters, 2015 - Elsevier
The main antitumor efficacy of irradiation relies in its direct cytotoxic effect. Increasing
evidence indicates a systemic effect of radiation though, mediated mainly by the immune …

[HTML][HTML] Neoadjuvant chemoradiotherapy for resectable esophageal carcinoma: a meta-analysis

HL Jin, H Zhu, TS Ling, HJ Zhang… - World journal of …, 2009 - ncbi.nlm.nih.gov
METHODS: We used MEDLINE and EMBASE databases to identify eligible studies and
manual searches were done to ensure no studies were missed. Trial validity assessment …

High metabolic rate and stem cell characteristics of esophageal cancer stem‐like cells depend on the Hsp27–AKT–HK2 pathway

CC Liu, KT Chou, JW Hsu, JH Lin… - … journal of cancer, 2019 - Wiley Online Library
Tumor progression with chemoresistance and local recurrence is commonly happened
during treatment of esophageal squamous cell carcinoma (ESCC). Cancer stem cells (CSC) …

Proteomics-based identification of autoantibody against heat shock protein 70 as a diagnostic marker in esophageal squamous cell carcinoma

Y Fujita, T Nakanishi, Y Miyamoto, M Hiramatsu… - Cancer letters, 2008 - Elsevier
Detection of novel tumor-related antigens and autoantibodies in cancer patients is expected
to facilitate the diagnosis of early-stage malignant tumor and establish effective new …

Identification of 5-fluorouracil response proteins in colorectal carcinoma cell line SW480 by two-dimensional electrophoresis and MALDI-TOF mass spectrometry

CSC Wong, VWK Wong, CML Chan… - Oncology …, 2008 - spandidos-publications.com
Colorectal cancer (CRC) is the second most prevalent cause of cancer-related deaths in the
Western world. 5-Fluorouracil (5-FU) is a standard chemotherapeutic drug to treat CRC …

[HTML][HTML] Prognostic significance of XIAP and NF-κB expression in esophageal carcinoma with postoperative radiotherapy

S Zhou, W Ye, Q Shao, Y Qi, M Zhang… - World journal of surgical …, 2013 - Springer
Background X-chromosome-linked IAP (XIAP) and nuclear factor-κB (NF-κB) are frequently
overexpressed and correlate closely with chemoradiotherapy resistance and poor prognosis …

Heat shock protein 27, a novel regulator of 5-fluorouracil resistance in colon cancer

M Tsuruta, H Nishibori, H Hasegawa… - Oncology …, 2008 - spandidos-publications.com
The resistance of colon cancer to 5-fluorouracil (5-FU) is a critical issue, and the cause of
this resistance cannot always be explained based on the known molecules. Heat shock …

Correlation of p53 status with the response to chemotherapy-based treatment in esophageal cancer: a meta-analysis

SS Zhang, QY Huang, H Yang, X Xie, KJ Luo… - Annals of surgical …, 2013 - Springer
Background The value of p53 status for predicting response to chemotherapy-based
treatment in patients with esophageal cancer has been controversial. We conducted a meta …