Introduction: Fractality is omnipresent in medicine and life sciences. In particular, the fractal
principle is found simultaneously at different organization levels of the cell nucleus. The aim …

Fractal characteristics of chromatin, revealed by light or electron microscopy, have been
reported during the last 20 years. Fractal features can easily be estimated in digitalized …

Laryngeal cancer is one of the most common malignant tumors in otolaryngology, and
histopathological image analysis is the gold standard for the diagnosis of laryngeal cancer …

In this book, we propose original perspectives in theoretical biology. We refer extensively to
physical methods of understanding phenomena but in an untraditional manner. At times, we …

Lacunarity, a quantitative morphological measure of how shapes fill space, and fractal
dimension, a morphological measure of the complexity of pixel arrangement, have shown …

Introduction Confocal laser endomicroscopy (CLE) is becoming a popular method for optical
biopsy of digestive mucosa for both diagnostic and therapeutic procedures. Computer aided …

Background Prognostic factors in malignant melanoma are currently based on clinical data
and morphologic examination. Other prognostic features, however, which are not yet used in …

Despite the large economic and intellectual efforts, cancer is still not easily treatable disease
by conventional therapies. This led ultimately to reconsider hyperthermia, like one of …

Pennes' bioheat equation is considered one of the most prevalent mathematical equations
used to estimate the temperature profile of a tumor in a human body when subjected to …

Objective Routine haematoxylin and eosin (H&E) photomicrographs from human
papillomavirus-associated oropharyngeal squamous cell carcinomas (HPV+ OpSCC) …