Factors influencing the decline in stroke mortality: a statement from the American Heart Association/American Stroke Association

DT Lackland, EJ Roccella, AF Deutsch, M Fornage… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Stroke mortality has been declining since the early 20th century.
The reasons for this are not completely understood, although the decline is welcome. As a …

Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials

AM Algra, PM Rothwell - The lancet oncology, 2012 - thelancet.com
Background Long-term follow-up of randomised trials of aspirin in prevention of vascular
events showed that daily aspirin reduced the incidence of colorectal cancer and several …

The role of aspirin in cancer prevention

MJ Thun, EJ Jacobs, C Patrono - Nature reviews Clinical oncology, 2012 - nature.com
Clinical guidelines for prophylactic aspirin use currently only consider the cardiovascular
benefits of aspirin, weighed against the potential harm from aspirin-induced bleeding. Daily …

[HTML][HTML] Estimates of benefits and harms of prophylactic use of aspirin in the general population

J Cuzick, MA Thorat, C Bosetti, PH Brown, J Burn… - Annals of …, 2015 - Elsevier
Background Accumulating evidence supports an effect of aspirin in reducing overall cancer
incidence and mortality in the general population. We reviewed current data and assessed …

Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies

E Flossmann, PM Rothwell - The Lancet, 2007 - thelancet.com
Background Randomised trials have shown that aspirin reduces the short-term risk of
recurrent colorectal adenomas in patients with a history of adenomas or cancer, but large …

[HTML][HTML] Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention

A Ornelas, N Zacharias-Millward, DG Menter… - Cancer and Metastasis …, 2017 - Springer
After more than a century, aspirin remains one of the most commonly used drugs in western
medicine. Although mainly used for its anti-thrombotic, anti-pyretic, and analgesic properties …

[HTML][HTML] Aspirin and cancer risk: a quantitative review to 2011

C Bosetti, V Rosato, S Gallus, J Cuzick, C La Vecchia - Annals of oncology, 2012 - Elsevier
Background Aspirin has been associated to a reduced risk of colorectal and possibly of a
few other common cancers. Methods To provide an up-to-date quantification of this …

Platelet “first responders” in wound response, cancer, and metastasis

DG Menter, S Kopetz, E Hawk, AK Sood… - Cancer and Metastasis …, 2017 - Springer
Platelets serve as “first responders” during normal wounding and homeostasis. Arising from
bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence …

Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung

RE Harris - Inflammopharmacology, 2009 - Springer
The existing epidemiologic literature was comprehensively reviewed to retrieve all
epidemiologic studies (case control and cohort studies) that examined exposure to …

Aspirin-based carbon dots, a good biocompatibility of material applied for bioimaging and anti-inflammation

X Xu, K Zhang, L Zhao, C Li, W Bu, Y Shen… - … applied materials & …, 2016 - ACS Publications
The emerging photoluminescent carbon-based nanomaterials are promising in various
fields besides cell imaging and carrier transport. Carbon nanomaterials with specific …