Factors influencing the decline in stroke mortality: a statement from the American Heart Association/American Stroke Association
DT Lackland, EJ Roccella, AF Deutsch, M Fornage… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Stroke mortality has been declining since the early 20th century.
The reasons for this are not completely understood, although the decline is welcome. As a …
The reasons for this are not completely understood, although the decline is welcome. As a …
Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials
AM Algra, PM Rothwell - The lancet oncology, 2012 - thelancet.com
Background Long-term follow-up of randomised trials of aspirin in prevention of vascular
events showed that daily aspirin reduced the incidence of colorectal cancer and several …
events showed that daily aspirin reduced the incidence of colorectal cancer and several …
The role of aspirin in cancer prevention
Clinical guidelines for prophylactic aspirin use currently only consider the cardiovascular
benefits of aspirin, weighed against the potential harm from aspirin-induced bleeding. Daily …
benefits of aspirin, weighed against the potential harm from aspirin-induced bleeding. Daily …
[HTML][HTML] Estimates of benefits and harms of prophylactic use of aspirin in the general population
Background Accumulating evidence supports an effect of aspirin in reducing overall cancer
incidence and mortality in the general population. We reviewed current data and assessed …
incidence and mortality in the general population. We reviewed current data and assessed …
Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies
E Flossmann, PM Rothwell - The Lancet, 2007 - thelancet.com
Background Randomised trials have shown that aspirin reduces the short-term risk of
recurrent colorectal adenomas in patients with a history of adenomas or cancer, but large …
recurrent colorectal adenomas in patients with a history of adenomas or cancer, but large …
[HTML][HTML] Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention
A Ornelas, N Zacharias-Millward, DG Menter… - Cancer and Metastasis …, 2017 - Springer
After more than a century, aspirin remains one of the most commonly used drugs in western
medicine. Although mainly used for its anti-thrombotic, anti-pyretic, and analgesic properties …
medicine. Although mainly used for its anti-thrombotic, anti-pyretic, and analgesic properties …
[HTML][HTML] Aspirin and cancer risk: a quantitative review to 2011
Background Aspirin has been associated to a reduced risk of colorectal and possibly of a
few other common cancers. Methods To provide an up-to-date quantification of this …
few other common cancers. Methods To provide an up-to-date quantification of this …
Platelet “first responders” in wound response, cancer, and metastasis
DG Menter, S Kopetz, E Hawk, AK Sood… - Cancer and Metastasis …, 2017 - Springer
Platelets serve as “first responders” during normal wounding and homeostasis. Arising from
bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence …
bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence …
Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
RE Harris - Inflammopharmacology, 2009 - Springer
The existing epidemiologic literature was comprehensively reviewed to retrieve all
epidemiologic studies (case control and cohort studies) that examined exposure to …
epidemiologic studies (case control and cohort studies) that examined exposure to …
Aspirin-based carbon dots, a good biocompatibility of material applied for bioimaging and anti-inflammation
The emerging photoluminescent carbon-based nanomaterials are promising in various
fields besides cell imaging and carrier transport. Carbon nanomaterials with specific …
fields besides cell imaging and carrier transport. Carbon nanomaterials with specific …