Medicinal mushroom modulators of molecular targets as cancer therapeutics

BZ Zaidman, M Yassin, J Mahajna… - Applied Microbiology and …, 2005 - Springer
Empirical approaches to discover anticancer drugs and cancer treatments have made
limited progress in the past several decades in finding a cure for cancer. The expanded …

[HTML][HTML] Natural products as adjunctive treatment for pancreatic cancer: recent trends and advancements

Q Yue, G Gao, G Zou, H Yu, X Zheng - BioMed research international, 2017 - hindawi.com
Pancreatic cancer is a type of common malignant tumors with high occurrence in the world.
Most patients presented in clinic had pancreatic cancer at advanced stages. Furthermore …

Targeting the DNA damage response in cancer

M Ljungman - Chemical reviews, 2009 - ACS Publications
US general Ulysses S. Grant once said:“The art of war is simple enough. Find out where
your enemy is. Get at him as soon as you can. Strike him as hard as you can.” The decision …

[PDF][PDF] Design and characterization of novel EphA2 agonists for targeted delivery of chemotherapy to cancer cells

B Wu, S Wang, SK De, E Barile, BA Quinn, I Zharkikh… - Chemistry & biology, 2015 - cell.com
The development of novel, targeted delivery agents for anti-cancer therapies requires the
design and optimization of potent and selective tumor-targeting agents that are stable and …

[HTML][HTML] The synergism of Clinacanthus nutans Lindau extracts with gemcitabine: downregulation of anti-apoptotic markers in squamous pancreatic ductal …

LW Hii, SHE Lim, CO Leong, SY Chin, NP Tan… - … and alternative medicine, 2019 - Springer
Background Clinacanthus nutans extracts have been consumed by the cancer patients with
the hope that the extracts can kill cancers more effectively than conventional …

[HTML][HTML] Fungal genetics, genomics, and secondary metabolites in pharmaceutical sciences

M Misiek, D Hoffmeister - Planta medica, 2007 - thieme-connect.com
Filamentous fungi produce a plethora of bioactive natural products. These metabolites
display a broad range of useful activities for pharmaceutical purposes, exemplified best by …

[HTML][HTML] Cyathus striatus Extract Induces Apoptosis in Human Pancreatic Cancer Cells and Inhibits Xenograft Tumor Growth In Vivo

L Sharvit, R Bar-Shalom, N Azzam, Y Yechiel… - Cancers, 2021 - mdpi.com
Simple Summary The main aim of the present study is to test the effect of Cyathus striatus
extract on the cell growth of human pancreatic cancer cells in vitro and in vivo. In addition …

[BOOK][B] Bioactive compounds from natural sources: Natural products as lead compounds in drug discovery

C Tringali - 2011 - books.google.com
The first edition of Bioactive Compounds from Natural Sources was published in a period of
renewed attention to biologically active compounds of natural origin. This trend has …

Caspase-mediated apoptosis and caspase-independent cell death induced by irofulven in prostate cancer cells

H Liang, RA Salinas, BZ Leal… - Molecular cancer …, 2004 - AACR
Irofulven (hydroxymethylacylfulvene) is a novel antitumor drug, which acts by alkylating
cellular macromolecular targets. The drug is a potent inducer of apoptosis in various types of …

Pancreatic cancer epidemiology

M Verma - Technology in cancer research & treatment, 2005 - journals.sagepub.com
Carcinoma of the exocrine pancreas remains a challenging disease mainly due to advanced
stage diagnosis, the early systemic dissemination, aggressive local tumor progression, and …