Crystal structure of abrin-a at 2.14 Å

TH Tahirov, TH Lu, YC Liaw, YL Chen, JY Lin - Journal of molecular biology, 1995 - Elsevier
The crystal structure of abrin-a, a type II ribosome-inactivating protein from the seeds
ofAbrus precatorius, has been determined from a novel crystalline form by the molecular …

[HTML][HTML] Bufalin induces apoptosis of human osteosarcoma U-2 OS cells through endoplasmic reticulum stress, caspase-and mitochondria-dependent signaling …

CH Lee, YL Shih, MH Lee, MK Au, YL Chen, HF Lu… - Molecules, 2017 - mdpi.com
Bone cancer is one of the cancer-related diseases, and there are increased numbers of
patients with bone cancer worldwide. Therefore the efficacy of treatment of bone cancer is …

[HTML][HTML] Cumulative use of therapeutic bladder anticholinergics and the risk of dementia in patients with lower urinary tract symptoms: a nationwide 12-year cohort …

YC Wang, YL Chen, CC Huang, CH Ho, YT Huang… - BMC geriatrics, 2019 - Springer
Background Studies have shown an association between lower urinary tract symptoms (LUTS)
and an increased risk of dementia. Whether anticholinergic use contributes to the …

Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme GBM 8401 cell migration and invasion via affecting NF‐κB and MMP‐2 and MMP‐9 …

CJ Chen, HS Shang, YL Huang, N Tien… - Environmental …, 2022 - Wiley Online Library
Human glioblastoma (GBM) is one of the common cancer death in adults worldwide, and its
metastasis will lead to difficult treatment. Finding compounds for future to develop treatment …

[HTML][HTML] Pathogenicity of avian polyomaviruses and prospect of vaccine development

CW Wang, YL Chen, SJT Mao, TC Lin, CW Wu… - Viruses, 2022 - mdpi.com
Polyomaviruses are nonenveloped icosahedral viruses with a double-stranded circular DNA
containing approximately 5000 bp and 5–6 open reading frames. In contrast to mammalian …

[HTML][HTML] Triptolide induced DNA damage in A375. S2 human malignant melanoma cells is mediated via reduction of DNA repair genes

FS Chueh, YL Chen, SC Hsu, JS Yang… - Oncology …, 2013 - spandidos-publications.com
Numerous studies have demonstrated that triptolide induces cell cycle arrest and apoptosis
in human cancer cell lines. However, triptolide-induced DNA damage and inhibition of DNA …

Fisetin induces apoptosis of HSC3 human oral cancer cells through endoplasmic reticulum stress and dysfunction of mitochondria-mediated signaling pathways

…, FM Hung, CH Lee, MY Yeh, MH Lee, HF Lu, YL Chen… - in vivo, 2017 - iv.iiarjournals.org
Background/Aim: Oral cancer has been reported to be one of the major cancer-related
diseases in human populations and the treatment of oral cancer is still unsatisfied. Fisetin, is a …

Anti‐interleukin‐6 receptor antibody inhibits the progression in human colon carcinoma cells

CP Hsu, YL Chen, CC Huang, CC Chou… - European journal of …, 2011 - Wiley Online Library
Eur J Clin Invest 2011; 41 (3): 277–284 Abstract Background Interleukin‐6 (IL‐6) promotes
proliferation and invasion in colorectal carcinoma, and serum IL‐6 levels are correlated with …

Sulforaphane‐induced apoptosis in human leukemia HL‐60 cells through extrinsic and intrinsic signal pathways and altering associated genes expression assayed …

…, SC Hsueh, JY Liu, NC Liao, YL Chen… - Environmental …, 2017 - Wiley Online Library
Sulforaphane (SFN), one of the isothiocyanates, is a biologically active compound extracted
from cruciferous vegetables, and has been shown to induce cytotoxic effects on many …

[HTML][HTML] Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase-and mitochondrial-dependent signaling …

FM Hung, YL Chen, AC Huang… - Oncology …, 2013 - spandidos-publications.com
Triptolide (TPL), a diterpene triepoxide compound, extracted from Tripterygium wilfordii Hook
F.[a traditional Chinese medicinal herb (TCM)], has demonstrated great chemotherapeutic …