Boron neutron capture therapy outcomes for advanced or recurrent head and neck cancer

…, S Haginomori, Y Sakurai, Y Kinashi… - Journal of radiation …, 2014 - academic.oup.com
We retrospectively review outcomes of applying boron neutron capture therapy (BNCT) to
unresectable advanced or recurrent head and neck cancers. Patients who were treated with …

First attempt of boron neutron capture therapy (BNCT) for hepatocellular carcinoma

…, S Hagiwara, S Masunaga, Y Kinashi… - Japanese Journal of …, 2007 - academic.oup.com
A 60-year-old man with multiple hepatocellular carcinomas (HCCs) was enrolled as the first
patient in a pilot study for treating multiple liver tumors with boron neutron capture therapy (…

The combined effect of boronophenylalanine and borocaptate in boron neutron capture therapy for SCCVII tumors in mice

K Ono, S Masunaga, M Suzuki, Y Kinashi… - International Journal of …, 1999 - Elsevier
Purpose: To increase the effect of boron neutron capture therapy (BNCT) on tumors in vivo,
the combined effects of para-boronophenylalanine (BPA) and borocaptate sodium (BSH) …

Radiobiological evidence suggesting heterogeneous microdistribution of boron compounds in tumors: its relation to quiescent cell population and tumor cure in …

K Ono, SI Masunaga, Y Kinashi… - … journal of radiation …, 1996 - europepmc.org
Purpose The heterogeneous microdistribution of boron compounds in tumors and its
significance on tumor cure were examined by a radiobiological procedure. The role of …

A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT)

…, H Kumada, H Kimura, S Masunaga, Y Kinashi… - Radiotherapy and …, 2008 - Elsevier
Two patients, one with malignant pleural mesothelioma and one with a malignant short
spindle cell tumor, received boron neutron capture therapy (BNCT). In each case, the tumors …

An alternative mechanism for radioprotection by dimethyl sulfoxide; possible facilitation of DNA double-strand break repair

…, M Suzuki, S Masunaga, Y Kinashi… - Journal of radiation …, 2010 - ieeexplore.ieee.org
The radioprotective effects of dimethyl sulfoxide (DMSO) have been known for many years,
and the suppression of hydroxyl (OH) radicals induced by ionizing radiation has been …

The effects of boron neutron capture therapy on liver tumors and normal hepatocytes in mice

M Suzuki, SI Masunaga, Y Kinashi… - Japanese journal of …, 2000 - Wiley Online Library
To explore the feasibility of employing boron neutron capture therapy (BNCT) to treat liver
tumors, the effects of BNCT were investigated by using liver tumor models and normal …

[HTML][HTML] FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ

…, LH Thompson, T Helleday, M Suzuki, Y Kinashi… - PloS one, 2011 - journals.plos.org
Nimustine (ACNU) and temozolomide (TMZ) are DNA alkylating agents which are commonly
used in chemotherapy for glioblastomas. ACNU is a DNA cross-linking agent and TMZ is a …

[HTML][HTML] DNA double-strand break induction in Ku80-deficient CHO cells following boron neutron capture reaction

Y Kinashi, S Takahashi, G Kashino, R Okayasu… - Radiation …, 2011 - Springer
Background Boron neutron capture reaction (BNCR) is based on irradiation of tumors after
accumulation of boron compound. B captures neutrons and produces an alpha ( 4 He) …

Feasibility of boron neutron capture therapy (BNCT) for malignant pleural mesothelioma from a viewpoint of dose distribution analysis

M Suzuki, Y Sakurai, S Masunaga, Y Kinashi… - International Journal of …, 2006 - Elsevier
Purpose: To investigate the feasibility of boron neutron capture therapy (BNCT) for
malignant pleural mesothelioma (MPM) from a viewpoint of dose distribution analysis using …