Aberrant WNT pathway signaling is an early progression event in 90% of colorectal cancers
1 . It occurs through mutations mainly of APC and less often of CTNNB1 (encoding β-catenin…

Recently, long noncoding RNAs (lncRNA) have emerged as new gene regulators and
prognostic markers in several cancers, including renal cell carcinoma (RCC). In this study, we …

Cutaneous lymphoma is a disease characterized with massive skin infiltration of lymphoid
malignant cells. They commonly express some T‐cell markers, such as CD2, CD3, CD4, and …

Recently miR-182 has been reported to be over-expressed in prostate cancer (PC) tissues,
however detailed functional analysis of miR-182-5p has not been carried out. The purpose of …

BNIP3 protein is a proapoptotic member of the Bcl-2 family that is expressed in hypoxic regions
of tumors. To examine its role in the progression of gastrointestinal cancer, we examined …

MUC1 is immunogenic in vivo and humoral and cellular immune responses against MUC1
have been detected in cancer patients. Our study explored the association of circulating anti‐…

Onco-miR-182-5p has been reported to be over-expressed in bladder cancer (BC) tissues
however a detailed functional analysis of miR-182-5p has not been carried out in BC. …

The functional significance of Wnt antagonist DKK1 has not been investigated in renal cell
carcinoma (RCC). Therefore, we hypothesized that DKK1 may be a tumor suppressor gene …

Wnt signaling pathways play important roles in tumorigenesis and are initiated by binding of
Wnt to various receptors including frizzleds (FZDs). FZDs are one of several families of …

We investigated whether one of the Wnt receptors, frizzled-7 (FZD7), functions in the canonical
Wnt signaling pathway of colorectal cancer (CRC) cells harboring an APC or CTNNB1 …