[HTML][HTML] Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis

Y Hirata, K Nomura, Y Senga, Y Okada, K Kobayashi… - JCI insight, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus is associated with various disorders of the locomotor system including the
decline in mass and function of skeletal muscle. The mechanism underlying this association …

[HTML][HTML] A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy

Y Hirata, K Nomura, D Kato… - The Journal of …, 2022 - Am Soc Clin Investig
Although immobility is a common cause of muscle atrophy, the mechanism underlying this
causality is unclear. We here show that Krüppel-like factor 15 (KLF15) and IL-6 are …

Association of hyperglycemia on admission and during hospitalization with mortality in diabetic patients admitted for pneumonia

Y Hirata, H Tomioka, R Sekiya, S Yamashita… - Internal …, 2013 - jstage.jst.go.jp
Objective Information available on the clinical features and outcomes of pneumonia in diabetic
patients is limited. There are no data on the association between glycemic control during …

Sodium–glucose cotransporter 2 inhibitors influence skeletal muscle pathology in patients with heart failure and reduced ejection fraction

N Wood, S Straw, CW Cheng, Y Hirata… - European Journal of …, 2024 - Wiley Online Library
Aims Patients with heart failure and reduced ejection fraction (HFrEF) exhibit skeletal
muscle pathology, which contributes to symptoms and decreased quality of life. Sodium–glucose …

A spectrophotometric biochemical oxygen demand determination method using 2, 6-dichlorophenolindophenol as the redox color indicator and the eukaryote …

H Nakamura, S Kobayashi, Y Hirata, K Suzuki… - Analytical …, 2007 - Elsevier
A method to determine the spectrophotometric biochemical oxygen demand (BOD sp ) was
studied with high sensitivity and reproducibility by employing 2,6-dichlorophenolindophenol (…

Changes in the Properties and Molecular Weights of Bacillus subtilis M-Type and N-Type α-Amylases Resulting from a Spontaneous Deletion

K YAMANE, Y HIRATA, T FURUSATO… - The Journal of …, 1984 - academic.oup.com
The regulatory gene, amyR2, and the structural gene, amyEn + , coding for N-type α-amylase
from Bacillus subtilis N7 have been cloned in the B. subtilis plasmid pUBHO. The complete …

Serum prognostic factors of androgen-deprivation therapy among Japanese men with de novo metastatic prostate cancer

T Kobayashi, R Namitome, YU Hirata… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: To date, several serum prognostic factors have been reported in metastatic
prostate cancer. In this study, we examined the prognostic value of these serum markers in …

Median-lower normal levels of serum thyroxine are associated with low triiodothyronine levels and body temperature in patients with central hypothyroidism

Y Hirata, H Fukuoka, G Iguchi… - European Journal of …, 2015 - academic.oup.com
Objective Although it has been recommended that serum free thyroxine (FT 4 ) levels should
be targeted to middle-upper normal levels during levothyroxine (l-T 4 ) replacement therapy …

[HTML][HTML] Prognostic significance of diabetes mellitus and dyslipidemia in men receiving androgen-deprivation therapy for metastatic prostate cancer

Y Hirata, M Shiota, T Kobayashi, E Kashiwagi… - Prostate …, 2019 - Elsevier
Objective The outcome of the androgen-deprivation therapy (ADT) may be affected by
metabolic diseases such as diabetes mellitus (DM) and dyslipidemia and/or by their treatments. …

Intraepidermal neutrophilic IgA pemphigus successfully treated with dapsone

Y Hirata, R Abe, K Kikuchi, A Hamasaka… - European Journal of …, 2012 - jle.com
Yu Hirata, Riichiro Abe, Kazuhiro Kikuchi, Asuka Hamasaka, Satoru Shinkuma,
Toshifumi Nomura, Wataru Nishie, Ken Arita, Hiroshi Shimizu … Auteur(s) : Yu Hirata …