[HTML][HTML] A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas
…, H Nakamura, Y Kanemura, Y Okita… - Acta neuropathologica …, 2016 - Springer
The prognostic impact of TERT mutations has been controversial in IDH-wild tumors, particularly
in glioblastomas (GBM). The controversy may be attributable to presence of potential …
in glioblastomas (GBM). The controversy may be attributable to presence of potential …
Slower growth of skull base meningiomas compared with non–skull base meningiomas based on volumetric and biological studies
N Hashimoto, CS Rabo, Y Okita, M Kinoshita… - Journal of …, 2012 - thejns.org
Object The precise natural history of incidentally discovered meningiomas (IDMs) remains
unknown. It has been reported that for symptomatic meningiomas, tumor location can be used …
unknown. It has been reported that for symptomatic meningiomas, tumor location can be used …
TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma
…, K Tamura, S Tanaka, F Higuchi, Y Okita… - Acta …, 2021 - Springer
The Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW)
update 3 recommends that histologic grade II and III IDH-wildtype diffuse …
update 3 recommends that histologic grade II and III IDH-wildtype diffuse …
[HTML][HTML] Lesion location implemented magnetic resonance imaging radiomics for predicting IDH and TERT promoter mutations in grade II/III gliomas
…, Y Narita, Y Terakawa, N Tsuyuguchi, Y Okita… - Scientific reports, 2018 - nature.com
Molecular biological characterization of tumors has become a pivotal procedure for glioma
patient care. The aim of this study is to build conventional MRI-based radiomics model to …
patient care. The aim of this study is to build conventional MRI-based radiomics model to …
[HTML][HTML] Radiomics and MGMT promoter methylation for prognostication of newly diagnosed glioblastoma
…, K Fujita, J Fukai, N Hayashi, Y Uematsu, Y Okita… - Scientific reports, 2019 - nature.com
We attempted to establish a magnetic resonance imaging (MRI)-based radiomic model for
stratifying prognostic subgroups of newly diagnosed glioblastoma (GBM) patients and …
stratifying prognostic subgroups of newly diagnosed glioblastoma (GBM) patients and …
[HTML][HTML] IDH1/2 mutation is a prognostic marker for survival and predicts response to chemotherapy for grade II gliomas concomitantly treated with radiation therapy
Y Okita, Y Narita, Y Miyakita… - International …, 2012 - spandidos-publications.com
Reliable prognostic biomarkers of grade II gliomas remain unclear. This study aimed to
examine the role of mutations of isocitrate dehydrogenase (IDH1/2), 1p/19q co-deletion, and …
examine the role of mutations of isocitrate dehydrogenase (IDH1/2), 1p/19q co-deletion, and …
[HTML][HTML] Prediction of IDH and TERT promoter mutations in low-grade glioma from magnetic resonance images using a convolutional neural network
…, Y Narita, Y Terakawa, N Tsuyuguchi, Y Okita… - Scientific reports, 2019 - nature.com
Identification of genotypes is crucial for treatment of glioma. Here, we developed a method
to predict tumor genotypes using a pretrained convolutional neural network (CNN) from …
to predict tumor genotypes using a pretrained convolutional neural network (CNN) from …
[HTML][HTML] Fine-tuning approach for segmentation of gliomas in brain magnetic resonance images with a machine learning method to normalize image differences …
…, H Arita, M Nonaka, T Uda, J Fukai, Y Okita… - Cancers, 2021 - mdpi.com
Simple Summary This study evaluates the performance degradation of machine learning
models for segmenting gliomas in brain magnetic resonance images caused by domain shift …
models for segmenting gliomas in brain magnetic resonance images caused by domain shift …
11C-methionine uptake correlates with tumor cell density rather than with microvessel density in glioma: a stereotactic image-histology comparison
Y Okita, M Kinoshita, T Goto, N Kagawa, H Kishima… - Neuroimage, 2010 - Elsevier
11 C-methionine positron emission tomography ( 11 C-methionine PET) provides accurate
detection of brain tumors. Several reports have analyzed the correlation between uptake of …
detection of brain tumors. Several reports have analyzed the correlation between uptake of …
[HTML][HTML] TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations
…, S Tamai, T Nakamura, T Uda, Y Okita… - Acta neuropathologica …, 2020 - Springer
TERT promoter mutations are commonly associated with 1p/19q codeletion in IDH-mutated
gliomas. However, whether these mutations have an impact on patient survival independent …
gliomas. However, whether these mutations have an impact on patient survival independent …