Previous studies have suggested that transepidermal water movement may play an important
role in epidermal homeostasis and barrier repair. Here we analyzed cutaneous barrier …

Members of the Smad proteins transmit signals triggered by the ligands of transforming
growth factor (TGF)-β superfamily. Ligand-activated receptors induce phosphorylation of so-…

INTRODUCTION: The purpose of this study was to assess the efficacy of instrumentation of
C-shaped canals with ProTaper rotary system and traditional instruments by using micro–…

Msx2 and Dlx5 are homeodomain proteins that play an important role in osteoblast differentiation
and whose expression is induced by bone morphogenetic proteins. Recently we have …

The tumor suppressor p53 plays a crucial role in the cellular response to DNA damage by
transcriptional activation of numerous downstream genes. Although a considerable number of …

Background: The apoptosis inhibitor survivin is one of the most specific proteins in breast
cancer patients. The role of this protein in predicting prognosis is still controversial. Patients …

Dlx5, a member of the Dlx family of homeodomain proteins, plays a critical role in bone
development and fracture healing. To understand the molecular mechanism underlying the …

Although the regulation of tumor angiogenesis is believed to be one of the core functions of
p53, the mechanism still remains to be elucidated. Here, we report that semaphorin 3F (…

Previous observations that vitamin D hormone induces the expression of the receptor activator
of nuclear factor κB (NF‐κB) ligand (RANKL), thereby stimulating osteoclastogenesis in …

In this research, rational design, synthesis, carbonic anhydrases (CAs) inhibitory effects,
and cytotoxicities of the 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-…