Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

…, CF Hsiao, JS Sung, JH Kim, YT Gao, YH Tsai… - Nature …, 2012 - nature.com
To identify common genetic variants that contribute to lung cancer susceptibility, we conducted
a multistage genome-wide association study of lung cancer in Asian women who never …

Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Parabacteroides goldsteinii lipopolysaccharide

…, YL Kuo, CJ Chang, TR Wu, CC Shu, YH Tsai… - Gut, 2022 - gut.bmj.com
Objective Chronic obstructive pulmonary disease (COPD) is a global disease characterised
by chronic obstruction of lung airflow interfering with normal breathing. Although the …

Circulating interleukin‐6 level is a prognostic marker for survival in advanced nonsmall cell lung cancer patients treated with chemotherapy

…, CF Hsiao, YM Yeh, GC Chang, YH Tsai… - … journal of cancer, 2013 - Wiley Online Library
Lung cancer is the leading cause of cancer death worldwide as well as in Taiwan. Interleukin‐6
(IL‐6) is a multifunctional cytokine and has been implicated in tumor progression. This …

[HTML][HTML] The 5p15. 33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia

…, YH Kim, H Shen, A Seow, M Yeager, YH Tsai… - PLoS …, 2010 - journals.plos.org
Genome-wide association studies of lung cancer reported in populations of European
background have identified three regions on chromosomes 5p15.33, 6p21.33, and 15q25 that …

[HTML][HTML] Chang Gung Research Database: A multi-institutional database consisting of original medical records

…, WC Chen, GH Chang, YT Tsai, PC Chen, YH Tsai - biomedical …, 2017 - Elsevier
Background The Chang Gung Research Database (CGRD) is a de-identified database
derived from original medical records of Chang Gung Memorial Hospital (CGMH), which …

[HTML][HTML] Afatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX …

…, YC Kim, CH Yang, TC Hsia, YM Chen, YH Tsai… - Annals of …, 2016 - Elsevier
Background Afatinib has demonstrated clinical benefit in patients with non-small-cell lung
cancer progressing after treatment with erlotinib/gefitinib. This phase III trial prospectively …

[HTML][HTML] Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

…, YH Kim, IJ Oh, VHF Lee, GC Chang, YH Tsai… - Nature …, 2023 - nature.com
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain
only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage …

Recovery of pulmonary functions, exercise capacity, and quality of life after pulmonary rehabilitation in survivors of ARDS due to severe influenza A (H1N1) …

…, HC Hu, KC Kao, NH Chen, YH Tsai… - Influenza and other …, 2018 - Wiley Online Library
Background Acute respiratory distress syndrome ( ARDS ) due to severe influenza A H1N1
pneumonitis would result in impaired pulmonary functions and health‐related quality of life ( …

Alpha-fetoprotein measurement benefits hepatocellular carcinoma surveillance in patients with cirrhosis

…, CH Shen, CH Lu, CS Wu, YH Tsai… - Official journal of the …, 2015 - journals.lww.com
OBJECTIVES: Liver cirrhosis is a major risk factor for hepatocellular carcinoma (HCC), and
all liver study societies recommend HCC surveillance in patients with cirrhosis. However, no …

Prediction of fluid responsiveness in acute respiratory distress syndrome patients ventilated with low tidal volume and high positive end-expiratory pressure

…, KC Kao, NH Chen, MJ Hsieh, YH Tsai - Critical care …, 2008 - journals.lww.com
Objective: Dynamic preload indicators with pulse pressure variation and stroke volume
variation are superior to static indicators for predicting fluid responsiveness in mechanically …