Background In December 2019, the coronavirus disease 2019 (COVID-19) outbreak occurred
in Wuhan. Data on the clinical characteristics and outcomes of patients with severe COVID…

Due to the biological importances of thiols, such as cysteine, homocysteine and glutathione,
the development of optical probes for thiols has been an active research area in recent few …

Due to the biological importance of amino acids, the development of optical probes for these
molecules has been an active research area in recent years. This tutorial review focuses on …

Drug discovery relies on the knowledge of not only drugs and targets, but also the
comparative agents and targets. These include poor binders and non-binders for developing …

In recent years, the development of methods to recognize and sense biologically and
environmentally important species has emerged as a significant target in the field of chemical …

Background Older patients with acute myeloid leukemia (AML) have a dismal prognosis,
even after treatment with a hypomethylating agent. Azacitidine added to venetoclax had …

Chromatin modifications, especially histone-tail acetylation, have been implicated in memory
formation. Increased histone-tail acetylation induced by inhibitors of histone deacetylases (…

Genotype imputation is commonly performed in genome-wide association studies because
it greatly increases the number of markers that can be tested for association with a trait. In …

Abstract Knowledge of therapeutic targets and early drug candidates is useful for improved
drug discovery. In particular, information about target regulators and the patented therapeutic …

Sensitive X-ray detection is crucial for medical diagnosis, industrial inspection and scientific
research. The recently described hybrid lead halide perovskites have demonstrated low-cost …