[HTML][HTML] Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide 3-kinase

S Kanda, Y Mochizuki, T Suematsu, Y Miyata… - Journal of Biological …, 2003 - ASBMB
Sonic hedgehog (Shh) acts as a morphogen in many cell types. Recent studies have shown
that hedgehog signaling is involved in vascular development as well as postnatal …

Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn

Y Mochizuki, T Nakamura, H Kanetake… - Journal of cell …, 2002 - journals.biologists.com
The angiopoietin (Ang)/Tie2 system is exclusively involved in vasculogenesis and angiogenesis.
Ang2 is known to inhibit Ang1-mediated phosphorylation of Tie2 as well as cellular …

Primary factors behind the heavy rain event of July 2018 and the subsequent heat wave in Japan

…, K Takemura, S Wakamatsu, H Togawa, Y Mochizuki… - Sola, 2019 - jstage.jst.go.jp
An extreme rainfall event occurred over western Japan and the adjacent Tokai region 26
mainly in early July, named “the Heavy Rain Event of July 2018”, which caused 27 widespread …

[HTML][HTML] AAV vector-mediated microdystrophin expression in a relatively small percentage of mdx myofibers improved the mdx phenotype

M Yoshimura, M Sakamoto, M Ikemoto, Y Mochizuki… - Molecular Therapy, 2004 - cell.com
Duchenne muscular dystrophy (DMD) is a lethal disorder of skeletal muscle caused by mutations
in the dystrophin gene. Adeno-associated virus (AAV) vector-mediated gene therapy is …

Pathological significance and prognostic role of microvessel density, evaluated using CD31, CD34, and CD105 in prostate cancer patients after radical prostatectomy …

…, K Mitsunari, A Asai, K Takehara, Y Mochizuki… - The …, 2015 - Wiley Online Library
BACKGROUND Neoadjuvant hormonal therapy (NHT) is performed to improve the outcome
in organ‐confined prostate cancer. However, there is little information regarding the …

A case of cat-to-human transmission of severe fever with thrombocytopenia syndrome virus

…, K Noguchi, K Maeda, Y Mochizuki… - Japanese Journal of …, 2019 - jstage.jst.go.jp
357 target region from the patient’s SFTSV (DDBJ/EMBL/GenBank accession number
LC433919) was identical to that from the cats’ SFTSVs (cats 2 and 3). These nt sequences were …

[HTML][HTML] Pathological characteristics of periodontal disease in patients with chronic kidney disease and kidney transplantation

M Kitamura, Y Mochizuki, Y Miyata, Y Obata… - International journal of …, 2019 - mdpi.com
Chronic kidney disease (CKD) is recognized as an irreversible reduction of functional
nephrons and leads to an increased risk of various pathological conditions, including …

[HTML][HTML] Periodontal disease in patients receiving dialysis

Y Miyata, Y Obata, Y Mochizuki, M Kitamura… - International journal of …, 2019 - mdpi.com
Chronic kidney disease (CKD) is characterized by kidney damage with proteinuria,
hematuria, and progressive loss of kidney function. The final stage of CKD is known as end-stage …

Effects of Vitamin D3-Binding Protein-Derived Macrophage Activating Factor (GcMAF) on Angiogenesis

S Kanda, Y Mochizuki, Y Miyata… - Journal of the …, 2002 - academic.oup.com
Background: The vitamin D 3 -binding protein (Gc protein)-derived macrophage activating
factor (GcMAF) activates tumoricidal macrophages against a variety of cancers indiscriminately…

Angiopoietin 1 is mitogenic for cultured endothelial cells

S Kanda, Y Miyata, Y Mochizuki, T Matsuyama… - Cancer research, 2005 - AACR
The angiopoietin (Ang)/Tie2 system is implicated in blood vessel formation and maturation.
However, the mitogenic effects of angiopoietins remain to be elucidated. Here, we show that …