Down-regulation of expression of interleukin-6 and its receptor results in growth inhibition of MCF-7 breast cancer cells

XP Jiang, DC Yang, RL Elliott, JF Head - Anticancer research, 2011 - ar.iiarjournals.org
Interleukin-6 (IL-6) plays an important role in the neoplastic process through its action on
cancer cell adhesion, motility, proliferation, tumor-specific antigen expression, and …

Reduction in serum IL-6 after vacination of breast cancer patients with tumour-associated antigens is related to estrogen receptor status

XP Jiang, DC Yang, RL Elliott, JF Head - Cytokine, 2000 - Elsevier
Elevated serum IL-6 concentrations have been associated with poor prognosis in a variety
of cancers, and decreases in serum IL-6 concentrations have been reported after …

Vaccination with a mixed vaccine of autogenous and allogeneic breast cancer cells and tumor associated antigens CA15-3, CEA and CA125-results in immune and …

XP Jiang, DC Yang, RL Elliott… - Cancer biotherapy & …, 2000 - liebertpub.com
In breast cancer there is often overexpression of the breast cancer antigen CA15-3, the
carcinoembryonic antigen (CEA) and the ovarian cancer antigen CA125, which makes them …

Decreased iron in cancer cells and their microenvironment improves cytolysis of breast cancer cells by natural killer cells

XP Jiang, RL Elliott - Anticancer Research, 2017 - ar.iiarjournals.org
The association of iron with anticancer immunity is unclear. In order to determine the role of
iron in anticancer immunity, we manipulated intracellular iron levels of the human MCF-7 …

[HTML][HTML] The adverse effect of gentamicin on cell metabolism in three cultured mammary cell lines:“Are cell culture data skewed?”

RL Elliott, XP Jiang - PloS one, 2019 - journals.plos.org
Many cells are cultured in media that contains an antibiotic to prevent bacterial contamination.
Mycoplasma and other bacterial contamination is a serious problem for those involved in …

Exogenous normal mammary epithelial mitochondria suppress glycolytic metabolism and glucose uptake of human breast cancer cells

XP Jiang, RL Elliott, JF Head - Breast Cancer Research and Treatment, 2015 - Springer
We hypothesized that normal mitochondria inhibited cancer cell proliferation and increased
drug sensitivity by the mechanism of suppression of cancer aerobic glycolysis. To …

[HTML][HTML] Mitochondrial Organelle Transplantation Is a Potential Therapeutic for Mitochondria Dysfunction in Severe Acute Respiratory Syndrome (SARS) Coronavirus …

CC Baucom, XP Jiang - Advances in Infectious Diseases, 2021 - scirp.org
COVID-19 severe symptoms and high mortality are mainly seen in elders with age-associated
diseases who have mitochondrial dysfunction. Mitochondrial dysfunction is a vulnerability …

[HTML][HTML] Mitochondria Dynamically Transplant into Cells in Vitro and in Mice and Rescue Aerobic Respiration of Mitochondrial DNA-Depleted Motor Neuron NSC-34

XP Jiang, CC Baucom, RL Elliott - Journal of Biomedical Science and …, 2020 - scirp.org
It has been reported that transplantation of pheochromocytoma P12 and hepatoma cells’
mitochondria improve the locomotive activity and prevent disease progress in experimental …

mRNA levels of nm23 in murine ascites hepatoma (H22) clones with different lymphatic metastatic potential

XP Jiang, ZY Tang, KD Liu, XD Zhou, ZY Lin… - Journal of cancer …, 1996 - Springer
Levels of expression of the nm23 gene inversely correlated with metastatic potential in
several rodent tumor model systems and human breast carcinoma. In the present study, we …

[PDF][PDF] Concern for Mitochondrial Transplantation in Humans:“Another Opinion”

RL Elliott, XP Jiang - 2020 - medtextpublications.com
In 2018, Edoardo Bertero et al published a paper in the Journal of Clinical Investigation
entitled Mitochondrial transplantation in humans:" magical" cure or cause for concern? The …