User profiles for WOOGWANG SIM

Woogwang Sim

University of California, San Francisco
Verified email at ucsf.edu
Cited by 34

Soluble TGFBI aggravates the malignancy of cholangiocarcinoma through activation of the ITGB1 dependent PPARγ signalling pathway

J Lee, J Lee, W Sim, JH Kim - Cellular Oncology, 2022 - Springer
Background Cholangiocarcinoma is a devastating cancer with a poor prognosis. Previous
reports have presented conflicting results on the role of transforming growth factor-β-induced …

[HTML][HTML] Methodical selected coptisine attenuates the malignancy of cholangiocarcinoma through the blockade of EGFR signalling

J Lee, J Lee, W Sim, JH Kim - Journal of Functional Foods, 2024 - Elsevier
The aim of the present study is to provide a methodical platform for the development of lead
compounds against cholangiocarcinoma. Coptisine was selected as a potential anti-cancer …

[HTML][HTML] Robust method for identification of prognostic gene signatures from gene expression profiles

W Sim, J Lee, C Choi - Scientific reports, 2017 - nature.com
Woogwang Sim and Jungsul Lee designed the IPP analysis and wrote the manuscript.
Jungsul Lee performed the collection and pre-processing of raw data. Woogwang Sim performed …

[HTML][HTML] Discovering the anti-cancer phytochemical rutin against breast cancer through the methodical platform based on traditional medicinal knowledge

J Lee, J Lee, WG Sim, JH Kim, C Choi, J Jeon - BMB reports, 2023 - ncbi.nlm.nih.gov
A number of therapeutic drugs have been developed from functional chemicals found in
plants. Knowledge of plants used for medicinal purposes has historically been transmitted by …

Eriodictyol Attenuates Cholangiocarcinoma Malignancy by Regulating HMOX1 Expression: An In Vitro Study

J Lee, W Sim, S Han, JH Byeon, SB Jin… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Cholangiocarcinoma remains one of the most dangerous types of cancer.
Eriodictyol is a well-known flavonoid having effective bioactivity against various malignant …

[HTML][HTML] Differential dependency of human pancreatic cancer cells on targeting PTEN via PLK 1 expression

J Lee, J Lee, W Sim, JH Kim - Cancers, 2020 - mdpi.com
Even though the tumour suppressive role of PTEN is well-known, its prognostic implications
are ambiguous. The objective of this study was to further explore the function of PTEN …

Rapid and quantitative measurement of cell adhesion and migration activity by time-series analysis on biomimetic topography

W Sim, J Cha, C Choi, K Choi - Biotechnology and Bioprocess …, 2017 - Springer
Glioblastoma Multiforme (GBM) is the most malignant brain tumor in adults, highly infiltrative
and difficult to cure. According to the histopathological evidence, the glioma cells are found …

[HTML][HTML] Assessing Spatial Distribution of Multicellular Self-Assembly Enables the Prediction of Phenotypic Heterogeneity in Glioblastoma

J Cha, W Sim, I Yong, J Park, JK Shim, JH Chang… - Cancers, 2022 - mdpi.com
Simple Summary The heterogeneity of tumors is one of the primary obstacles to successful
treatment. Although the examination of tumor heterogeneity is essential for comprehending …

Prognostic factor identification from continuous variable by improvement of log-rank test

W Sim - 2018 - koasas.kaist.ac.kr
In this research, a prognostic score calculation, “Iterative Patients Partitioning (IPP)” is
suggested as an effective method to identify prognostic factor. Prognostic factor can be used in …

[HTML][HTML] Portraits of breast cancer progression

GS Dalgin, G Alexe, D Scanfeld, P Tamayo… - BMC …, 2007 - Springer
Background Clustering analysis of microarray data is often criticized for giving ambiguous
results because of sensitivity to data perturbation or clustering techniques used. In this paper, …