Genome-wide mutational signatures of aristolochic acid and its application as a screening tool
Aristolochic acid (AA), a natural product of Aristolochia plants found in herbal remedies and
health supplements, is a group 1 carcinogen that can cause nephrotoxicity and upper …
health supplements, is a group 1 carcinogen that can cause nephrotoxicity and upper …
Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
…, PH Lin, CK Chuang, YH Chang, WH Weng… - Science translational …, 2017 - science.org
Trithorax-like group complex containing KDM6A acts antagonistically to Polycomb-repressive
complex 2 (PRC2) containing EZH2 in maintaining the dynamics of the repression and …
complex 2 (PRC2) containing EZH2 in maintaining the dynamics of the repression and …
[HTML][HTML] Mutation signatures implicate aristolochic acid in bladder cancer development
…, A Gan, SS Myint, EY Siew, LD Ler, LG Ng, WH Weng… - Genome medicine, 2015 - Springer
Background Aristolochic acid (AA) is a natural compound found in many plants of the
Aristolochia genus, and these plants are widely used in traditional medicines for numerous …
Aristolochia genus, and these plants are widely used in traditional medicines for numerous …
Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas
WH Weng, J Åhlén, K Åström, WO Lui… - Clinical Cancer …, 2005 - AACR
Purpose: Ezrin is a cytoskeleton linker protein that is actively involved in regulating the
growth and metastatic capacity of cancer cells. It has recently been reported to be involved in …
growth and metastatic capacity of cancer cells. It has recently been reported to be involved in …
Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma
…, J Wejde, O Brosjö, A Von Rosen, WH Weng… - Clinical cancer …, 2005 - AACR
Purpose: To evaluate known and suggested prognostic markers, especially insulin-like
growth factor type 1 receptor (IGF-1R), in highly malignant soft tissue sarcomas (STS). …
growth factor type 1 receptor (IGF-1R), in highly malignant soft tissue sarcomas (STS). …
Glucose/glutathione co-triggered tumor hypoxia relief and Chemodynamic therapy to enhance Photothermal therapy in bladder cancer
…, KJ Yu, JW Jhou, HH Pang, WH Weng… - ACS Applied Bio …, 2021 - ACS Publications
Photothermal therapy (PTT) is a potential treatment for cancer that makes use of near-infrared
(NIR) laser irradiation and is expected to assist traditional anti-cancer drug therapies; …
(NIR) laser irradiation and is expected to assist traditional anti-cancer drug therapies; …
[HTML][HTML] High-sensitivity dual-probe detection of urinary miR-141 in cancer patients via a modified screen-printed carbon electrode-based electrochemical biosensor
…, SX Weng, YL Lin, YE Chiou, ST Pang, WH Weng - Sensors, 2021 - mdpi.com
The screening and diagnosis of cancer are hallmarks of medicine in the aging population.
Recently, microRNAs have shown potential for use as biomarkers, which could advance the …
Recently, microRNAs have shown potential for use as biomarkers, which could advance the …
Combined detection of cancer cells and a tumor biomarker using an immunomagnetic sensor for the improvement of prostate-cancer diagnosis
…, SS Liao, YT Chen, HC Chen, WH Weng… - Advanced …, 2014 - ntut.elsevierpure.com
Capture and detection of both a relevant antigen and cancer cells are demonstrated using
magnetic graphene oxide (MGO) possessing conjugated antibodies. By simply dropping the …
magnetic graphene oxide (MGO) possessing conjugated antibodies. By simply dropping the …
[HTML][HTML] Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression
WH Weng, WH Leung, YJ Pang… - Oncology …, 2016 - spandidos-publications.com
EGFR-inhibitor (Cetuximab) is one of the main targeted drugs used for metastatic colorectal
carcinoma (CRC). The benefit from Cetuximab appears to be limited to a subtype of patients, …
carcinoma (CRC). The benefit from Cetuximab appears to be limited to a subtype of patients, …
[PDF][PDF] Neuregulin/erythroblastic leukemia viral oncogene homolog 3 autocrine loop contributes to invasion and early recurrence of human hepatoma
Intrahepatic metastasis is the primary cause of the high recurrence and poor prognosis of
human hepatocellular carcinoma (HCC). However, neither its molecular mechanisms nor …
human hepatocellular carcinoma (HCC). However, neither its molecular mechanisms nor …