Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic variants, …

High mobility group A (HMGA) proteins play an important role in the regulation of transcription,
differentiation, and neoplastic transformation. In this work, the expression of HMGA 1 and …

The development of tyrosine kinase inhibitor treatments has made it important to test cancer
patients for clinically significant gene mutations that influence the benefit of treatment. …

Recent studies have shown the important role of microRNAs (miRNAs) in a variety of
biological processes, and in its ability to distinguish tumors according to their prognostic and …

Purpose: To identify microRNAs (miRNA) that predict response to anti-EGFR antibodies in
patients with wild-type KRAS metastatic colorectal cancer (mCRC). Experimental Design: …

Background Microbial ecosystems that inhabit the human gut form central component of our
physiology and metabolism, regulating and modulating both health and disease. Changes …

Osteosarcoma (OS) is an aggressive bone tumor that mainly affects children and adolescents.
OS has a strong tendency to relapse and metastasize, resulting in poor prognosis and …

Anti-EGFR monoclonal antibodies (anti-EGFRmAb) serve in the treatment of metastatic
colorectal cancer (mCRC), but patients with a mutation in KRAS/BRAF and nearly one-half of …

Pancreatic cancer (PC) is an aggressive disease with a high mortality and poor prognosis.
The human microbiome is a key factor in many malignancies, having the ability to alter host …

Colorectal cancer (CRC) is the third most common malignancy and the second most common
cause of cancer death worldwide. Early detection of CRC can improve patient survival …