Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …

Some recent clinical and preclinical evidence suggests that neuroinflammation is a key
factor that interacts with the three neurobiological correlates of major depressive disorder: …

Importance Amyloid-β positron emission tomography (PET) imaging allows in vivo detection
of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its …

Background/Aims: The aim of this study was to identify neuropsychiatric subsyndromes of
the Neuropsychiatric Inventory in a large sample of outpatients with Alzheimer’s disease (AD). …

Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described
hallmarks of Alzheimer's disease, but their relationships are poorly understood. The …

Purpose Positron emission tomography (PET) imaging of brain amyloid load has been
suggested as a core biomarker for Alzheimer’s disease (AD). The aim of this study was to test the …

Importance One characteristic histopathological event in Alzheimer disease (AD) is cerebral
amyloid aggregation, which can be detected by biomarkers in cerebrospinal fluid (CSF) and …

Cognitive deficits are well documented in psychiatric disorders, particularly in schizophrenia
and depression. Cognitive activity roots in perceptions. However, research on sensorial …

Major depressive disorder is a debilitating disease. Unfortunately, treatment with antidepressants
(ADs) has limited therapeutic efficacy since resistance to AD is common. Research in …

Background/Aims: The aim of this study was to determine the consistency of neuropsychiatric
subsyndromes of the Neuropsychiatric Inventory across several clinical and demographic …