Cancer genomic, transcriptomic, and proteomic profiling has generated extensive data that
necessitate the development of tools for its analysis and dissemination. We developed …

In all organisms, heat-shock proteins (HSPs) provide an ancient defense system. These
proteins act as molecular chaperones by assisting proper folding and refolding of misfolded …

Purpose Current prognostic factors are poor at identifying patients at risk of disease
recurrence after surgery for stage II colon cancer. Here we describe a DNA microarray–based …

Breast cancer progression is associated with aberrant DNA methylation and expression of
genes that control the epithelial-mesenchymal transition (EMT), a critical step in malignant …

Over the past four decades in the United States, there has been a divergent trend in mortality
rates between African-Americans and Caucasians with colorectal cancer (CRC). Rates …

The products of bcl‐2 and p53 genes are involved in the regulation of apoptosis and proliferation
and have been associated with prognosis in several malignancies, including colorectal …

Pseudoangiomatous stromal hyperplasia (PASH) is a benign mesenchymal proliferative
lesion of the breast. In 2005, only 109 cases had been reported since its initial description in …

Purpose: MicroRNAs (miRNA) have potential prognostic value for colorectal cancers; however,
their value based on patient race/ethnicity and pathologic stage has not been determined…

Correlation of elevated levels of the lipogenic enzyme, fatty acid synthase (FASE), with
advanced stages of some cancers has drawn attention to this enzyme as a possible marker of …

Biomarkers play an essential role in the management of patients with invasive cancers.
Pancreatic ductal adenocarcinoma (PDC) associated with poor prognosis due to advanced …