Microvascular invasion of single small hepatocellular carcinoma≤ 3 cm: predictors and optimal treatments

Y Yamashita, K Imai, T Yusa, Y Nakao… - Annals of …, 2018 - Wiley Online Library
Background Small hepatocellular carcinomas ( HCC ≤3 cm) are generally considered to
have low malignant potential; however, some of them display pathological microvascular …

Clinical significance of PD-L1 expression in both cancer and stroma cells of cholangiocarcinoma patients

…, Y Yamashita, Y Nakao, R Itoyama, T Yusa… - Annals of Surgical …, 2020 - Springer
Background The clinical significance of programmed death 1 and its ligand (PD-L1) as
therapeutic targets has been reported previously. This study aimed to investigate the clinical …

Microvascular invasion in small-sized hepatocellular carcinoma: significance for outcomes following hepatectomy and radiofrequency ablation

K Imai, YI Yamashita, T Yusa, Y Nakao… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: The significance of microvascular invasion (MVI) of hepatocellular
carcinoma (HCC) after radiofrequency ablation (RFA) is unknown. Patients and Methods: We …

Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer

…, T Akiyama, K Yamashita, Y Nakao, T Yusa… - Cancer letters, 2021 - Elsevier
Cancer cells craftily adapt their energy metabolism to their microenvironment. Nutrient
deprivation due to hypovascularity and fibrosis is a major characteristic of pancreatic ductal …

Survival impact of immune cells infiltrating peritumoral area of hepatocellular carcinoma

T Yusa, Y Yamashita, H Okabe, Y Nakao… - Cancer …, 2022 - Wiley Online Library
Inflammatory and immune cells in the tumor microenvironment are reported to be associated
with tumor progression in several cancers. In total, 225 patients who underwent initial and …

[HTML][HTML] Ectopic hepatocellular carcinoma mimicking a retroperitoneal tumor: a case report

Y Adachi, H Hayashi, T Yusa, T Takematsu… - World Journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND An ectopic hepatocellular carcinoma (EHCC) arises from the ectopic liver
which is defined as a hepatic organ or tissue not connected to surrounding tissues. EHCC is a …

Clinical role of fludeoxyglucose (18F) positron emission tomography/computed tomography (18F-FDG PET/CT) in patients with pancreatic neuroendocrine tumors

T Matsumoto, H Okabe, Y Yamashita, T Yusa… - Surgery Today, 2019 - Springer
Purposes Clinical predictive markers for the malignant potential of pancreatic neuroendocrine
tumors (PNETs) are limited without histological investigation. We reported previously that …

The pivotal predictor of severe postoperative complications of pancreatoduodenectomy: complex links of bacterial contamination from preoperative biliary drainage

R Itoyama, H Okabe, Y Nakao, T Yusa, S Nakagawa… - Surgery today, 2020 - Springer
Purpose Preoperative biliary drainage (PBD) prior to pancreatoduodenectomy (PD) is
controversial. The aim of this study was to clarify how PBD leads to postoperative complications of …

Perioperative allogeneic blood transfusion does not influence patient survival after hepatectomy for hepatocellular carcinoma: a propensity score matching analysis

…, F Kitamura, N Uemura, Y Nakao, T Yusa… - World Journal of …, 2019 - Springer
Background Whether perioperative allogeneic blood transfusion (PABT) negatively influences
patient survival after hepatectomy (HR) for hepatocellular carcinoma (HCC) remains …

Clinical usefulness of perioperative C-reactive protein/albumin ratio in patients with intrahepatic cholangiocarcinoma: a retrospective single institutional study

…, K Arima, T Miyata, R Itoyama, T Yusa… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Prognoses of patients with cancer can be predicted on the basis of preoperative
nutrition- or inflammation-based scores; however, predicting the prognostic impact of …